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metaplastic cell transformation

Known as: Transforming, Cellular Transformation, Cell Transformation 
The conversion of a cell from a normal phenotype, which undergoes a limited number of mitotic divisions, into an aberrant phenotype that is immortal… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Pattern Recognition Receptors (PRRs) are proteins capable of recognizing molecules frequently found in pathogens (the so-called… Expand
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Review
2018
Review
2018
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy known as adult T-cell leukemia (ATL… Expand
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Review
2018
Review
2018
Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been… Expand
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Review
2012
Review
2012
The local microenvironment, or niche, of a cancer cell plays important roles in cancer development. A major component of the… Expand
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Review
2004
Review
2004
Phosphatidylinositol-3 kinases, PI3Ks, constitute a lipid kinase family characterized by their ability to phosphorylate inositol… Expand
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Review
2000
Review
2000
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract STATs are latent transcription factors that mediate cytokine- and growth factor–directed transcription. In many human… Expand
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Highly Cited
1997
Highly Cited
1997
NIH 3T3 fibroblasts stably transformed with a constitutively active isoform of p21Ras, H-RasV12 (v-H-Ras or EJ-Ras), produced… Expand
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Review
1994
Review
1994
Multiple genetic changes occur during the evolution of normal cells into cancer cells. This evolution is facilitated in cancer… Expand
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Highly Cited
1991
Highly Cited
1991
The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could… Expand
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