metaplastic cell transformation

Known as: Transforming, Cellular Transformation, Cell Transformation 
The conversion of a cell from a normal phenotype, which undergoes a limited number of mitotic divisions, into an aberrant phenotype that is immortal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
05010015019472017

Papers overview

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Highly Cited
2014
Highly Cited
2014
The immune system influences the fate of developing cancers by not only functioning as a tumour promoter that facilitates… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNAs (miRNAs) belong to a recently discovered class of small RNA molecules that regulate gene expression at the post… (More)
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Highly Cited
2009
Highly Cited
2009
MicroRNAs (miRNAs) have emerged as key post-transcriptional regulators of gene expression, involved in diverse physiological and… (More)
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Highly Cited
2007
Highly Cited
2007
MicroRNAs (miRNAs) are a new class of small noncoding RNAs that post-transcriptionally regulate the expression of target mRNA… (More)
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Highly Cited
2006
Highly Cited
2006
Endogenous small RNAs (miRNAs) regulate gene expression by mechanisms conserved across metazoans. While the number of verified… (More)
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Highly Cited
2003
Highly Cited
2003
ErbB2 is a receptor tyrosine kinase whose activity in normal cells depends on dimerization with another ligand-binding ErbB… (More)
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Highly Cited
1999
Highly Cited
1999
STATs are latent transcription factors that mediate cytokine- and growth factor-directed transcription. In many human cancers and… (More)
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Highly Cited
1997
Highly Cited
1997
NIH 3T3 fibroblasts stably transformed with a constitutively active isoform of p21(Ras), H-RasV12 (v-H-Ras or EJ-Ras), produced… (More)
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Highly Cited
1994
Highly Cited
1994
Caveolae are 50-100-nm membrane microdomains that represent a subcompartment of the plasma membrane. Previous morphological… (More)
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Highly Cited
1991
Highly Cited
1991
The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could… (More)
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