Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Phorbols

Known as: Phorbols [Chemical/Ingredient], phorbol 
The parent alcohol of the tumor promoting compounds from CROTON OIL (Croton tiglium).
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Tuberous sclerosis complex (TSC) is a genetic disorder caused by mutations in either of the two tumor suppressor genes TSC1 or… Expand
Is this relevant?
Review
2003
Review
2003
The evolutionarily conserved actions of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), in yeast, plants and mammals… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
We have studied activation by phorbol derivatives of TRPV4 channels, the human VRL-2, and murine TRP12 channels, which are highly… Expand
Is this relevant?
Review
1999
Review
1999
Natural products afford a window of opportunity to study important biology. If the natural product is used or abused by human… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We determined whether resveratrol, a phenolic antioxidant found in grapes and other food products, inhibited phorbol ester (PMA… Expand
  • figure 2
  • figure 5
  • figure 4
  • figure 6
  • figure 7
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Sphingosine inhibited protein kinase C activity and phorbol dibutyrate binding. When the mechanism of inhibition of activity and… Expand
Is this relevant?
Highly Cited
1986
Highly Cited
1986
ICAM-1 is a cell surface glycoprotein originally defined by a monoclonal antibody (MAb) that inhibits phorbol ester-stimulated… Expand
Is this relevant?
Highly Cited
1983
Highly Cited
1983
The phorbol diester receptor present in the particulate fraction of rat brain was solubilized by divalent ion chelation in the… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Although the biochemical mechanism of action of phorbol ester tumour promoters is not fully understood, it is known that phorbol… Expand
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Tumor-promoting phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA) directly activate in vitro Ca2+-activated… Expand
Is this relevant?