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Phorbols

Known as: Phorbols [Chemical/Ingredient], phorbol 
The parent alcohol of the tumor promoting compounds from CROTON OIL (Croton tiglium).
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (12)

14-deoxylactucinPhorbolPhorbol EstersTetradecanoylphorbol Acetate

Broader (3)

CarcinogensDiterpenesTumor Promoters
Croton Oilaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Highly Cited
1992
Highly Cited
1992
Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.
Highly Cited
1991
Highly Cited
1991
Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C.
Highly Cited
1989
Highly Cited
1989
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
We have investigated the effects of ligation of the fibronectin receptor (FnR) on gene expression in rabbit synovial fibroblasts… 
Highly Cited
1988
Highly Cited
1988
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.
Okadaic acid is a polyether compound of a C38 fatty acid, isolated from a black sponge, Halichondria okadai. Previous studies… 
Highly Cited
1986
Highly Cited
1986
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.
Highly Cited
1986
Highly Cited
1986
Cloning and expression of multiple protein kinase C cDNAs
Highly Cited
1984
Highly Cited
1984
Growth factors immediately raise cytoplasmic free Ca2+ in human fibroblasts.
Highly Cited
1982
Highly Cited
1982
Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin.
Cultures consisting almost entirely of human melanocytes were obtained from epidermal single-cell suspensions by using phorbol 12… 
Highly Cited
1979
Highly Cited
1979
Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.
When suspension cultures of human promyelocytic leukemia cells (line HL60) were treated with 12-O-tetradecanoylphorbol 13-acetate… 
Highly Cited
1979
Highly Cited
1979
Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells.
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