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Tetradecanoylphorbol Acetate
Known as:
Myristate Acetate, Phorbol
, Phorbol 13-Acetate, 12-O-Tetradecanoyl
, PMA (phorbol myristate acetate)
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A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic…
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National Institutes of Health
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Related topics
Related topics
13 relations
Narrower (2)
12-O-tetradecanoylphorbol-1,3-acetate
phorbolol myristate acetate
Broader (2)
Carcinogens
Phorbols
In Blood
NCIt Antineoplastic Agent Terminology
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Sphingosine-1-phosphate: an enigmatic signalling lipid
S. Spiegel
,
S. Milstien
Nature Reviews Molecular Cell Biology
2003
Corpus ID: 22622224
The evolutionarily conserved actions of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), in yeast, plants and mammals…
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Highly Cited
1991
Highly Cited
1991
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing.
E. Tischer
,
R. Mitchell
,
+4 authors
J. Abraham
The Journal of biological chemistry
1991
Corpus ID: 20654829
Highly Cited
1989
Highly Cited
1989
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
M. Kobayashi
,
L. Fitz
,
+7 authors
G. Trinchieri
The Journal of experimental medicine
1989
Corpus ID: 9242838
We have identified and purified a novel cytokine, NK cell stimulatory factor (NKSF), from the cell-free supernatant fluid of the…
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Highly Cited
1988
Highly Cited
1988
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.
A. Ding
,
C. Nathan
,
D. Stuehr
Journal of immunology
1988
Corpus ID: 6554806
The capacity of 12 cytokines to induce NO2- or H2O2 release from murine peritoneal macrophages was tested by using resident…
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Highly Cited
1988
Highly Cited
1988
Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate.
M. Huang
,
R. Smart
,
C. Q. Wong
,
A. Conney
Cancer research
1988
Corpus ID: 8591797
The effects of topically applied curcumin, chlorogenic acid, caffeic acid, and ferulic acid on 12-O-tetradecanoylphorbol-13…
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Highly Cited
1987
Highly Cited
1987
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
P. Angel
,
M. Imagawa
,
+6 authors
M. Karin
Cell
1987
Corpus ID: 23154076
Highly Cited
1986
Highly Cited
1986
Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
Michael Loran Dustin
,
R. Rothlein
,
A. Bhan
,
C. Dinarello
,
T. Springer
Journal of immunology
1986
Corpus ID: 21941984
ICAM-1 is a cell surface glycoprotein originally defined by a monoclonal antibody (MAb) that inhibits phorbol ester-stimulated…
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Review
1984
Review
1984
The role of protein kinase C in cell surface signal transduction and tumour promotion
Y. Nishizuka
Nature
1984
Corpus ID: 4240505
Protein kinase C has a crucial role in signal transduction for a variety of biologically active substances which activate…
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Highly Cited
1983
Highly Cited
1983
Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
J. Gerdes
,
U. Schwab
,
H. Lemke
,
H. Stein
International journal of cancer
1983
Corpus ID: 1764319
The production of a mouse monoclonal antibody, Ki‐67, is described. The Ki‐67 antibody recognized a nuclear antigen present in…
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Highly Cited
1982
Highly Cited
1982
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
M. Castagna
,
Y. Takai
,
K. Kaibuchi
,
K. Sano
,
U. Kikkawa
,
Y. Nishizuka
The Journal of biological chemistry
1982
Corpus ID: 38067723
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