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Tetradecanoylphorbol Acetate

Known as: Myristate Acetate, Phorbol, Phorbol 13-Acetate, 12-O-Tetradecanoyl, PMA (phorbol myristate acetate) 
A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic… Expand
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (2)

12-O-tetradecanoylphorbol-1,3-acetatephorbolol myristate acetate

Broader (2)

CarcinogensPhorbols
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives
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Papers overview

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Review
2017
Review
2017
In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review
BACKGROUND Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation (NETosis) have been described. Since there… Expand
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Highly Cited
2004
Highly Cited
2004
Guideline to reference gene selection for quantitative real-time PCR.
Today, quantitative real-time PCR is the method of choice for rapid and reliable quantification of mRNA transcription. However… Expand
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Review
2003
Review
2003
Sphingosine-1-phosphate: an enigmatic signalling lipid
The evolutionarily conserved actions of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), in yeast, plants and mammals… Expand
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Highly Cited
1991
Highly Cited
1991
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing.
Vascular endothelial growth factor (VEGF) is an apparently endothelial cell-specific mitogen that is structurally related to… Expand
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Highly Cited
1989
Highly Cited
1989
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
We have identified and purified a novel cytokine, NK cell stimulatory factor (NKSF), from the cell-free supernatant fluid of the… Expand
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Highly Cited
1988
Highly Cited
1988
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.
The capacity of 12 cytokines to induce NO2- or H2O2 release from murine peritoneal macrophages was tested by using resident… Expand
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Highly Cited
1988
Highly Cited
1988
Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate.
The effects of topically applied curcumin, chlorogenic acid, caffeic acid, and ferulic acid on 12-O-tetradecanoylphorbol-13… Expand
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Highly Cited
1986
Highly Cited
1986
Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
ICAM-1 is a cell surface glycoprotein originally defined by a monoclonal antibody (MAb) that inhibits phorbol ester-stimulated… Expand
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Highly Cited
1983
Highly Cited
1983
Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation.
The production of a mouse monoclonal antibody, Ki-67, is described. The Ki-67 antibody recognized a nuclear antigen present in… Expand
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Highly Cited
1983
Highly Cited
1983
Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.
We have developed a quantitative assay to monitor the oxidative burst (H2O2 production) of polymorphonuclear leukocytes (PMNL… Expand
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