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Tetradecanoylphorbol Acetate

Known as: Myristate Acetate, Phorbol, Phorbol 13-Acetate, 12-O-Tetradecanoyl, PMA (phorbol myristate acetate) 
A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
  • A. Newton
  • Critical reviews in biochemistry and molecular…
  • 2018
  • Corpus ID: 3716456
Abstract Protein kinase C (PKC) isozymes belong to a family of Ser/Thr kinases whose activity is governed by reversible release… Expand
Review
2003
Review
2003
The evolutionarily conserved actions of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), in yeast, plants and mammals… Expand
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Highly Cited
1991
Highly Cited
1991
Vascular endothelial growth factor (VEGF) is an apparently endothelial cell-specific mitogen that is structurally related to… Expand
Highly Cited
1989
Highly Cited
1989
We have identified and purified a novel cytokine, NK cell stimulatory factor (NKSF), from the cell-free supernatant fluid of the… Expand
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Highly Cited
1988
Highly Cited
1988
The capacity of 12 cytokines to induce NO2- or H2O2 release from murine peritoneal macrophages was tested by using resident… Expand
Highly Cited
1988
Highly Cited
1988
The effects of topically applied curcumin, chlorogenic acid, caffeic acid, and ferulic acid on 12-O-tetradecanoylphorbol-13… Expand
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Highly Cited
1987
Highly Cited
1987
The promoter regions of several phorbol diester-(TPA-) inducible genes (collagenase, stromelysin, hMT IIA, and SV40) share a… Expand
Highly Cited
1986
Highly Cited
1986
ICAM-1 is a cell surface glycoprotein originally defined by a monoclonal antibody (MAb) that inhibits phorbol ester-stimulated… Expand
Review
1984
Review
1984
Protein kinase C has a crucial role in signal transduction for a variety of biologically active substances which activate… Expand
Highly Cited
1983
Highly Cited
1983
The production of a mouse monoclonal antibody, Ki‐67, is described. The Ki‐67 antibody recognized a nuclear antigen present in… Expand