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Phorbol Esters

Known as: Esters, Phorbol, Phorbol Ester, Phorbol Esters [Chemical/Ingredient] 
Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighboring carbon atoms are esterified to fatty acids. The commonest of… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (33)

12-O-benzyloxymethylphorbol-13-decanoate12-O-methoxymethylphorbol-13-decanoate12-O-retinoylphorbol-13-acetate12-deoxyphorbol 13-isobutyrate

Broader (2)

CarcinogensPhorbols
Croton Oilaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Heterogeneity of protein kinase C-mediated rapid regulation of Na/K-ATPase in kidney epithelial cells.
Highly Cited
1992
Highly Cited
1992
Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells.
Highly Cited
1992
Highly Cited
1992
Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines.
The effects of the protein kinase C (PKC) activators, phorbol ester 12-O-tetradecanoyl-13-phorbol acetate (TPA) and the marine… 
Highly Cited
1991
Highly Cited
1991
Vasoconstrictor‐induced protein‐tyrosine phosphorylation in cultured vascular smooth muscle cells
Highly Cited
1991
Highly Cited
1991
β1 Integrin‐mediated lymphocyte adherence to extracellular matrix is enhanced by phorbol ester treatment
The interaction of the human T cell leukemia, Jurkat, with the extracellular matrix components collagen and fibronectin was… 
Review
1989
Review
1989
Modulation of protein kinase C and diverse cell functions by sphingosine--a pharmacologically interesting compound linking sphingolipids and signal transduction.
Highly Cited
1989
Highly Cited
1989
Protein kinase C is involved in laminin stimulation of neurite outgrowth
Highly Cited
1989
Highly Cited
1989
The role of phosphorylation and limited proteolytic cleavage of talin and vinculin in the disruption of focal adhesion integrity.
Highly Cited
1986
Highly Cited
1986
The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid.
The Ca2+/phospholipid-dependent protein kinase (protein kinase C) of human neutrophils is converted to a proteolytically modified… 
Highly Cited
1977
Highly Cited
1977
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
Summary Topical application of retinoic acid to mouse skin led to a dramatic inhibition of phorbol ester (12- O -tetradecanoyl… 
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