Phorbol Esters

Known as: Esters, Phorbol, Phorbol Ester, Phorbol Esters [Chemical/Ingredient] 
Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighboring carbon atoms are esterified to fatty acids. The commonest of… (More)
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Phorbol esters are the tetracyclic diterpenoids generally known for their tumor promoting activity. The phorbol esters mimic the… (More)
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Highly Cited
2004
Highly Cited
2004
Tuberous sclerosis complex (TSC) is a genetic disorder caused by mutations in either of the two tumor suppressor genes TSC1 or… (More)
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Highly Cited
1998
Highly Cited
1998
We determined whether resveratrol, a phenolic antioxidant found in grapes and other food products, inhibited phorbol ester (PMA… (More)
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Highly Cited
1997
Highly Cited
1997
The chemokine receptor CXCR4 is required, together with CD4, for entry by some isolates of HIV-1, particularly those that emerge… (More)
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Highly Cited
1996
Highly Cited
1996
Caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives, is known to have antimitogenic… (More)
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Highly Cited
1989
Highly Cited
1989
The morphology and kinetics of pinocytosis by bone marrow-derived macrophages were studied to determine how stimulation by… (More)
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Highly Cited
1987
Highly Cited
1987
The promoter regions of several phorbol diester-(TPA-) inducible genes (collagenase, stromelysin, hMT IIA, and SV40) share a… (More)
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Highly Cited
1986
Highly Cited
1986
Protein kinase C (PKC), a calcium-dependent phospholipid-sensitive kinase which is selectively activated by phorbol esters, is… (More)
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Highly Cited
1983
Highly Cited
1983
Although the biochemical mechanism of action of phorbol ester tumour promoters is not fully understood, it is known that phorbol… (More)
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Highly Cited
1983
Highly Cited
1983
A tumor-promoting phorbol ester, [3H]phorbol-12,13-dibutyrate, may bind to a homogeneous preparation of Ca2+-activated… (More)
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