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Phorbol Esters

Known as: Esters, Phorbol, Phorbol Ester, Phorbol Esters [Chemical/Ingredient] 
Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighboring carbon atoms are esterified to fatty acids. The commonest of… Expand
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Tuberous sclerosis complex (TSC) is a genetic disorder caused by mutations in either of the two tumor suppressor genes TSC1 or… Expand
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Review
2001
Review
2001
A plethora of physiological and pathological stimuli induce and activate a group of DNA binding proteins that form AP-1 dimers… Expand
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Highly Cited
1998
Highly Cited
1998
We determined whether resveratrol, a phenolic antioxidant found in grapes and other food products, inhibited phorbol ester (PMA… Expand
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Highly Cited
1995
Highly Cited
1995
Protein kinase Cs (PKCs) are a ubiquitous family of regulatory enzymes that associate with membranes and are activated by… Expand
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Highly Cited
1994
Highly Cited
1994
High levels of immunoreactive cyclooxygenase (Cox; prostaglandin H synthase) are present in synovia from patients with rheumatoid… Expand
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Highly Cited
1987
Highly Cited
1987
The promoter regions of several phorbol diester-(TPA-) inducible genes (collagenase, stromelysin, hMT IIA, and SV40) share a… Expand
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Highly Cited
1986
Highly Cited
1986
Protein kinase C (PKC), a calcium-dependent phospholipid-sensitive kinase which is selectively activated by phorbol esters, is… Expand
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Highly Cited
1983
Highly Cited
1983
Although the biochemical mechanism of action of phorbol ester tumour promoters is not fully understood, it is known that phorbol… Expand
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Highly Cited
1983
Highly Cited
1983
A tumor-promoting phorbol ester, [3H]phorbol-12,13-dibutyrate, may bind to a homogeneous preparation of Ca2+-activated… Expand
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Highly Cited
1982
Highly Cited
1982
Cultures consisting almost entirely of human melanocytes were obtained from epidermal single-cell suspensions by using phorbol 12… Expand
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