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Phorbol

National Institutes of Health

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Phorbols

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isophorbol

Papers overview

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2006
2006
Identification of potent, selective protein kinase C inhibitors based on a phorbol skeleton.
The elucidation of specific functions of protein kinase C (PKC) subtypes in physiological processes is an important challenge for… 
Highly Cited
2002
Highly Cited
2002
Oligomerization through Hemopexin and Cytoplasmic Domains Regulates the Activity and Turnover of Membrane-type 1 Matrix Metalloproteinase*
The formation of multimeric complexes by membrane-type 1 matrix metalloproteinase (MT1-MMP) may facilitate its autocatalytic… 
2000
2000
GLAST: gene expression regulation by phorbol esters
The gene expression regulation of the Na+-dependent high affinity glutamate/aspartate transporter GLAST expressed in cultured… 
2000
2000
Protein kinase C-gamma phorbol-binding domain involved in protein-protein interaction.
Protein kinase C-gamma (PKC-gamma) contains two cysteine-rich regions (Cys1, Cys2) responsible for interaction with phospholipids… 
2000
2000
Sp1-like activity mediates angiotensin-II-induced plasminogen-activator inhibitor type-1 (PAI-1) gene expression in mesangial cells.
Angiotensin II (Ang II) up-regulates plasminogen-activator inhibitor type-1 (PAI-1) expression in mesangial cells to enhance… 
1999
1999
Intensification of growth factor receptor signalling by phorbol treatment of ligand-primed cells implies a dimer-stabilizing effect of protein kinase C-dependent juxtamembrane domain phosphorylation.
Highly Cited
1998
Highly Cited
1998
TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I.
A northwestern screen of a CHO-K1 cell line cDNA library with radiolabelled HIV-1 TAR RNA identified a novel TAR RNA interacting… 
Highly Cited
1997
Highly Cited
1997
Interactions between Protein Kinase C and Pleckstrin Homology Domains
Pleckstrin homology (PH) domains comprised of loosely conserved sequences of ∼100 amino acid residues are a functional protein… 
1995
1995
Characterization of novel phorbol ester‐ and serum‐responsive sequences of the rat ornithine decarboxylase gene promoter
Ornithine decarboxylase (a), the key regulatory enzyme in mammalian polyamine biosynthesis, is rapidly induced by mitogens and… 
Highly Cited
1990
Highly Cited
1990
Neuritogenesis in cerebellar granule cells in vitro: a role for protein kinase C.
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