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Transforming Growth Factors
Known as:
Factor, Transforming Growth
, Growth Factor, Transforming
, TGF
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Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture…
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National Institutes of Health
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Related topics
Related topics
43 relations
Artemin, human
BMP2 protein, human
BMP3 protein, human
BMP5 protein, human
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Narrower (7)
Bone Morphogenetic Proteins
Transforming Growth Factor Beta 2
Transforming Growth Factor alpha
Transforming Growth Factor beta
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Broader (1)
Growth Substances
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β
Kazuhiko Nakamura
,
A. Kitani
,
W. Strober
Journal of Experimental Medicine
2001
Corpus ID: 17309014
CD4+CD25+ T cells have been identified as a population of immunoregulatory T cells, which mediate suppression of CD4+CD25− T…
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Review
2000
Review
2000
Role of transforming growth factor beta in human disease.
G. Blobe
,
W. Schiemann
,
H. Lodish
New England Journal of Medicine
2000
Corpus ID: 9595401
In human tissues, normal homeostasis requires intricately balanced interactions between cells and the network of secreted…
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Highly Cited
1994
Highly Cited
1994
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.
K. Polyak
,
J. Kato
,
+4 authors
A. Koff
Genes & Development
1994
Corpus ID: 10612782
Cell-cell contact and TGF-beta can arrest the cell cycle in G1. Mv1Lu mink epithelial cells arrested by either mechanism are…
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Highly Cited
1993
Highly Cited
1993
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
A. Kulkarni
,
C. Huh
,
+7 authors
S. Karlsson
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 7626125
To delineate specific developmental roles of transforming growth factor beta 1 (TGF-beta 1) we have disrupted its cognate gene in…
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Highly Cited
1993
Highly Cited
1993
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
A. Desmoulière
,
A. Geinoz
,
F. Gabbiani
,
G. Gabbiani
Journal of Cell Biology
1993
Corpus ID: 7582404
Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and biochemical features of smooth muscle (SM…
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Review
1990
Review
1990
The transforming growth factor-beta family.
J. Massagué
Annual Review of Cell Biology
1990
Corpus ID: 35109826
Highly Cited
1987
Highly Cited
1987
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.
S. Wahl
,
D. Hunt
,
+4 authors
M. Sporn
Proceedings of the National Academy of Sciences…
1987
Corpus ID: 29724321
Recent studies have focused on the potential role of transforming growth factor type beta (TGF-beta) as an immunoregulatory…
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Highly Cited
1986
Highly Cited
1986
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
R. Ignotz
,
J. Massagué
Journal of Biological Chemistry
1986
Corpus ID: 24860480
We have examined whether the extracellular matrix is a biochemical target for transforming growth factor-beta (TGFbeta). We find…
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Highly Cited
1986
Highly Cited
1986
Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth
J. Kehrl
,
L. Wakefield
,
+5 authors
A. Fauci
Journal of Experimental Medicine
1986
Corpus ID: 16529834
This study examines the potential role of transforming growth factor beta (TGF-beta) in the regulation of human T lymphocyte…
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Highly Cited
1981
Highly Cited
1981
New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.
A. Roberts
,
M. Anzano
,
L. C. Lamb
,
J. M. Smith
,
M. Sporn
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 23276262
Proteins potentiated by epidermal growth factor (EGF) to induce a transformed phenotype in non-neoplastic rat kidney fibroblasts…
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