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Transforming Growth Factors

Known as: Factor, Transforming Growth, Growth Factor, Transforming, TGF 
Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture… 
National Institutes of Health

Related topics

Related topics

43 relations
Artemin, humanBMP2 protein, humanBMP3 protein, humanBMP5 protein, human

Narrower (7)

Bone Morphogenetic ProteinsTransforming Growth Factor Beta 2Transforming Growth Factor alphaTransforming Growth Factor beta

Broader (1)

Growth Substances

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Inhibition of Transforming Growth Factor (TGF)- 1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF- Type I Receptor Kinase Activity: SB-431542
Transforming growth factor 1 (TGF1) is a potent fibrotic factor responsible for the synthesis of extracellular matrix. TGF1 acts… 
Highly Cited
2001
Highly Cited
2001
Genetic programs of epithelial cell plasticity directed by transforming growth factor-β
Epithelial–mesenchymal transitions (EMTs) are an essential manifestation of epithelial cell plasticity during morphogenesis… 
Highly Cited
1993
Highly Cited
1993
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.
Recently the cDNA encoding interleukin 13 (IL-13), a T-cell-derived cytokine, was cloned and expressed. The present study… 
Highly Cited
1990
Highly Cited
1990
Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur
We have investigated the ability of exogenous transforming growth factor-beta (TGF-beta) to induce osteogenesis and… 
Highly Cited
1990
Highly Cited
1990
Negative regulation of transforming growth factor-beta by the proteoglycan decorin.
Decorin is a small chondroitin-dermatan sulphate proteoglycan consisting of a core protein and a single glycosaminoglycan chain… 
Highly Cited
1988
Highly Cited
1988
Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.
An important event during wound healing is the contraction of newly formed connective tissue (granulation tissue) by fibroblasts… 
Highly Cited
1986
Highly Cited
1986
Type beta transforming growth factor is an inhibitor of myogenic differentiation.
We have investigated the effect of type beta transforming growth factor (TGF-beta) on the differentiation of skeletal muscle… 
Highly Cited
1985
Highly Cited
1985
Type beta transforming growth factor: a bifunctional regulator of cellular growth.
Type beta transforming growth factor (TGF-beta) is a two-chain polypeptide of 25,000 daltons isolated from many tissues… 
Highly Cited
1984
Highly Cited
1984
Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor.
Purified growth inhibitor from BSC-1 cells and type beta transforming growth factor from human platelets are shown to have nearly… 
Highly Cited
1984
Highly Cited
1984
Rat transforming growth factor type 1: structure and relation to epidermal growth factor.
The complete amino acid sequence of rat transforming growth factor type 1 has been determined. This growth factor, obtained from… 
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