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Transforming Growth Factor alpha
Known as:
Transforming Growth Factor alpha [Chemical/Ingredient]
, transforming growth factor alpha (TGF alpha)
, TGFalpha
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An EPIDERMAL GROWTH FACTOR related protein that is found in a variety of tissues including EPITHELIUM, and maternal DECIDUA. It is synthesized as a…
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National Institutes of Health
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Related topics
Related topics
17 relations
In Blood
Process of secretion
TGFA gene
Transforming growth factor alpha Ag:PrThr:Pt:Tiss:Ord:Immune stain
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Narrower (5)
Shope fibroma virus growth factor
TGFA protein, human
transforming growth factor alpha-Pseudomonas exotoxin A (40)
transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38)
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Broader (1)
Transforming Growth Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Metalloproteinase-dependent Transforming Growth Factor-α Release Mediates Neurotensin-stimulated MAP Kinase Activation in Human Colonic Epithelial Cells*
Dezheng Zhao
,
Yanai Zhan
,
+4 authors
C. Pothoulakis
Journal of Biological Chemistry
2004
Corpus ID: 25054335
Expression of the neuropeptide neurotensin (NT) and its high affinity receptor (NTR1) is increased during the course of…
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Highly Cited
2003
Highly Cited
2003
Modulation of Estrogen Receptor α Function and Stability by Tamoxifen and a Critical Amino Acid (Asp-538) in Helix 12*
S. Pearce
,
Hong Liu
,
V. Jordan
Journal of Biological Chemistry
2003
Corpus ID: 25739403
Estrogen receptor α (ER) is a ligand-activated transcription factor implicated in breast cancer growth. Selective estrogen…
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Highly Cited
2003
Highly Cited
2003
Epiregulin is more potent than EGF or TGFα in promoting in vitro wound closure due to enhanced ERK/MAPK activation
B. K. Draper
,
T. Komurasaki
,
M. Davidson
,
L. Nanney
Journal of Cellular Biochemistry
2003
Corpus ID: 24643892
Epiregulin (EPR) is a broad specificity EGF family member that activates ErbB1 and ErbB4 homodimers and all possible…
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Highly Cited
1997
Highly Cited
1997
EGF receptor activation stimulates endogenous gastrin gene expression in canine G cells and human gastric cell cultures.
Michael G. Ford
,
J. D. Valle
,
C. Soroka
,
J. Merchant
Journal of Clinical Investigation
1997
Corpus ID: 32604962
Gastrin release from the antral gastrin-expressing cell (G cell) is regulated by bombesin and luminal factors. Yet, these same…
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Highly Cited
1995
Highly Cited
1995
Multiple genetic alterations in malignant metastatic insulinomas
K. Pavelić
,
R. Hrašćan
,
+5 authors
T. Čabrijan
Journal of Pathology
1995
Corpus ID: 25808713
Proto‐oncogenes, growth factors/receptors, and tumour suppressor genes were analysed in malignant metastatic insulinomas. Normal…
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Highly Cited
1991
Highly Cited
1991
Transforming growth factor alpha contributes to the mechanism by which hypothalamic injury induces precocious puberty.
M. Junier
,
Y. Ma
,
M. Costa
,
G. Hoffman
,
D. Hill
,
S. Ojeda
Proceedings of the National Academy of Sciences…
1991
Corpus ID: 45473612
It has long been known that lesions of the hypothalamus lead to female sexual precocity. While an increased production of…
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Highly Cited
1989
Highly Cited
1989
Transforming Growth Factor-α Expression in the Anterior Pituitary Gland: Regulation by Epidermal Growth Factor and Phorbol Ester in Dispersed Cells
S. Mueller
,
M. Kobrin
,
A. Paterson
,
J. Kudlow
1989
Corpus ID: 25254014
We have previously reported the immunohistochemical localization of transforming growth factor-α (TGFα) in the intact bovine…
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Highly Cited
1988
Highly Cited
1988
Transforming growth factors produced by normal and neoplastically transformed rat liver epithelial cells in culture.
Chientzu Liu
,
Ming-Sound Tsao
,
J. Grisham
Cancer Research
1988
Corpus ID: 7324871
The secretion of transforming growth factors (TGFs) alpha and beta by normal, chemically transformed, and malignant rat liver…
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Highly Cited
1988
Highly Cited
1988
Interleukin-1 in combination with transforming growth factor-alpha produces enhanced bone resorption in vitro.
J. Lorenzo
,
S. Sousa
,
M. Centrella
Endocrinology
1988
Corpus ID: 39222318
Interleukin-1 (IL-1) and transforming growth factor-alpha (TGF alpha) both stimulate bone resorption. We examined the effects…
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Highly Cited
1987
Highly Cited
1987
Expression of transforming growth factor alpha (TGF alpha) in differentiated rat mammary tumors: estrogen induction of TGF alpha production.
Sue C. Liu
,
Brunella Sanfilippo
,
Isabelle Perroteau
,
Rik Derynck
,
D. S. Salomon
,
W. Kidwell
Molecular Endocrinology
1987
Corpus ID: 22544507
Primary well-differentiated dimethylbenzene alpha-anthracene (DMBA)-or nitrosomethylurea (NMU)-induced rat mammary…
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