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Transforming Growth Factor alpha

Known as: Transforming Growth Factor alpha [Chemical/Ingredient], transforming growth factor alpha (TGF alpha), TGFalpha 
An EPIDERMAL GROWTH FACTOR related protein that is found in a variety of tissues including EPITHELIUM, and maternal DECIDUA. It is synthesized as a… Expand
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
We report the crystal structure, at 2.5 A resolution, of a truncated human EGFR ectodomain bound to TGFalpha. TGFalpha interacts… Expand
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Highly Cited
2001
Highly Cited
2001
The polytopic membrane protein Rhomboid-1 promotes the cleavage of the membrane-anchored TGFalpha-like growth factor Spitz… Expand
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Highly Cited
1999
Highly Cited
1999
Goblet-cell hyperplasia is a critical pathological feature in hypersecretory diseases of airways. However, the underlying… Expand
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Highly Cited
1999
Highly Cited
1999
Exposure of A431 squamous and MDA-MB-231 mammary carcinoma cells to ionizing radiation has been associated with short transient… Expand
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Highly Cited
1999
Highly Cited
1999
Targeted mice lacking functional EGF or amphiregulin (AR) were derived and bred to the TGFalpha-knockout to generate mice lacking… Expand
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Highly Cited
1998
Highly Cited
1998
The ectodomains of numerous proteins are released from cells by proteolysis to yield soluble intercellular regulators. The… Expand
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Highly Cited
1998
Highly Cited
1998
Growth factors may play an important role in tumour growth and angiogenesis by their influence on tumour cell proliferation or… Expand
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Highly Cited
1997
Highly Cited
1997
The adult mammalian forebrain subependyma contains neural stem cells and their progeny, the constitutively proliferating… Expand
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Highly Cited
1993
Highly Cited
1993
The squamous mucosa of patients who develop head and neck cancer is "condemned" or predisposed to disregulated growth as… Expand
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Highly Cited
1989
Highly Cited
1989
We investigated whether transforming growth factor alpha (TGF-alpha) is involved in hepatocyte growth responses both in vivo and… Expand
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