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Transforming Growth Factor alpha

Known as: Transforming Growth Factor alpha [Chemical/Ingredient], transforming growth factor alpha (TGF alpha), TGFalpha 
An EPIDERMAL GROWTH FACTOR related protein that is found in a variety of tissues including EPITHELIUM, and maternal DECIDUA. It is synthesized as a… 
National Institutes of Health

Related topics

Related topics

17 relations
In BloodProcess of secretionTGFA geneTransforming growth factor alpha Ag:PrThr:Pt:Tiss:Ord:Immune stain

Narrower (5)

Shope fibroma virus growth factorTGFA protein, humantransforming growth factor alpha-Pseudomonas exotoxin A (40)transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38)

Broader (1)

Transforming Growth Factors

Papers overview

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Highly Cited
2004
Highly Cited
2004
Metalloproteinase-dependent Transforming Growth Factor-α Release Mediates Neurotensin-stimulated MAP Kinase Activation in Human Colonic Epithelial Cells*
Expression of the neuropeptide neurotensin (NT) and its high affinity receptor (NTR1) is increased during the course of… 
Highly Cited
2003
Highly Cited
2003
Modulation of Estrogen Receptor α Function and Stability by Tamoxifen and a Critical Amino Acid (Asp-538) in Helix 12*
Estrogen receptor α (ER) is a ligand-activated transcription factor implicated in breast cancer growth. Selective estrogen… 
Highly Cited
2003
Highly Cited
2003
Epiregulin is more potent than EGF or TGFα in promoting in vitro wound closure due to enhanced ERK/MAPK activation
Epiregulin (EPR) is a broad specificity EGF family member that activates ErbB1 and ErbB4 homodimers and all possible… 
Highly Cited
1997
Highly Cited
1997
EGF receptor activation stimulates endogenous gastrin gene expression in canine G cells and human gastric cell cultures.
Gastrin release from the antral gastrin-expressing cell (G cell) is regulated by bombesin and luminal factors. Yet, these same… 
Highly Cited
1995
Highly Cited
1995
Multiple genetic alterations in malignant metastatic insulinomas
Proto‐oncogenes, growth factors/receptors, and tumour suppressor genes were analysed in malignant metastatic insulinomas. Normal… 
Highly Cited
1991
Highly Cited
1991
Transforming growth factor alpha contributes to the mechanism by which hypothalamic injury induces precocious puberty.
It has long been known that lesions of the hypothalamus lead to female sexual precocity. While an increased production of… 
Highly Cited
1989
Highly Cited
1989
Transforming Growth Factor-α Expression in the Anterior Pituitary Gland: Regulation by Epidermal Growth Factor and Phorbol Ester in Dispersed Cells
We have previously reported the immunohistochemical localization of transforming growth factor-α (TGFα) in the intact bovine… 
Highly Cited
1988
Highly Cited
1988
Transforming growth factors produced by normal and neoplastically transformed rat liver epithelial cells in culture.
The secretion of transforming growth factors (TGFs) alpha and beta by normal, chemically transformed, and malignant rat liver… 
Highly Cited
1988
Highly Cited
1988
Interleukin-1 in combination with transforming growth factor-alpha produces enhanced bone resorption in vitro.
Interleukin-1 (IL-1) and transforming growth factor-alpha (TGF alpha) both stimulate bone resorption. We examined the effects… 
Highly Cited
1987
Highly Cited
1987
Expression of transforming growth factor alpha (TGF alpha) in differentiated rat mammary tumors: estrogen induction of TGF alpha production.
Primary well-differentiated dimethylbenzene alpha-anthracene (DMBA)-or nitrosomethylurea (NMU)-induced rat mammary… 
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