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TGFA gene

Known as: TGFA, TRANSFORMING GROWTH FACTOR, ALPHA, transforming growth factor alpha 
This gene is involved in angiogenesis and mitogenesis.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Proliferation Regulatory ProcessHomo sapiensPancreatic carcinomaReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Gene involvement in cleft lip and palate (CLP) patients
It is supposed that the most frequent birth defect worldwide is clefts of the lip and/or palate (CL+-P). The frequency is non… 
2010
2010
MTHFR, TGFB3, and TGFA polymorphisms and their association with the risk of non‐syndromic cleft lip and cleft palate in China
Our previous results indicated a moderate association between the methylenetetrahydrofolate reductase (MTHFR) gene 677C‐T variant… 
Highly Cited
2004
Highly Cited
2004
Targeted scan of fifteen regions for nonsyndromic cleft lip and palate in Filipino families
Cleft lip with or without cleft palate (CL/P) is a congenital anomaly with variable birth prevalence based on geographic origins… 
Highly Cited
2003
Highly Cited
2003
Variants of developmental genes (TGFA, TGFB3, and MSX1) and their associations with orofacial clefts: A case‐parent triad analysis
We selected 262 case‐parent triads from a population‐based study of orofacial clefts in Norway, and examined variants of… 
Highly Cited
2003
Highly Cited
2003
Cleft palate, transforming growth factor alpha gene variants, and maternal exposures: Assessing gene‐environment interactions in case‐parent triads
We have previously reported a threefold risk of cleft palate only (CPO) among children homozygous for the less common allele A2… 
Highly Cited
1999
Highly Cited
1999
Transforming growth factor-alpha (TGFA): genomic structure, boundary sequences, and mutation analysis in nonsyndromic cleft lip/palate and cleft palate only.
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or… 
Highly Cited
1997
Highly Cited
1997
Transforming growth factor α locus and nonsyndromic cleft lip with or without cleft palate: A reappraisal
An association between nonsyndromic cleft lip with or without cleft palate (CL±P) and genetic variation at the transforming… 
Highly Cited
1995
Highly Cited
1995
Association study of transforming growth factor alpha (TGF alpha) TaqI polymorphism and oral clefts: indication of gene-environment interaction in a population-based sample of infants with birth…
In this study of infants with isolated birth defects, 69 cleft palate only cases, 114 cleft lip with or without cleft palate… 
Highly Cited
1991
Highly Cited
1991
Further evidence for an association between genetic variation in transforming growth factor alpha and cleft lip and palate.
Ardinger et al. (1989) hypothesized that there might be a nonrandom association between clefting and RFLPs of candidate genes… 
Highly Cited
1990
Highly Cited
1990
Characterization of the rat transforming growth factor alpha gene and identification of promoter sequences
We have determined the complete nucleotide sequence of rat transforming growth factor alpha (TGF alpha) mRNA and characterized… 
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