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Transforming Growth Factor beta
Known as:
TGFbeta
, Milk Growth Factor
, Transforming growth factors-beta
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A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a…
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National Institutes of Health
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Related topics
Related topics
31 relations
Cell Differentiation process
Cell Proliferation Regulatory Process
Extracellular Space
GDNF protein, human
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Narrower (9)
Vg1 protein, Xenopus
betaIG-H3 protein
dvr1 protein, zebrafish
fugacin
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Involvement of Calcineurin in Transforming Growth Factor-β-mediated Regulation of Extracellular Matrix Accumulation*
J. Gooch
,
Y. Gorin
,
Bin-Xian Zhang
,
H. Abboud
Journal of Biological Chemistry
2004
Corpus ID: 39386346
Calcineurin is a calcium-dependent, serine/threonine phosphatase that functions as a signaling intermediate. In this study, we…
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Highly Cited
1999
Highly Cited
1999
Glial Cell Line-Derived Neurotrophic Factor Rescues Target-Deprived Sympathetic Spinal Cord Neurons But Requires Transforming Growth Factor-β as Cofactor In Vivo
A. Schober
,
R. Hertel
,
+5 authors
K. Unsicker
Journal of Neuroscience
1999
Corpus ID: 11618072
Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor for several populations of CNS and peripheral…
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Highly Cited
1998
Highly Cited
1998
Potent suppression of IL‐12 production from monocytes and dendritic cells during endotoxin tolerance
C. Karp
,
M. Wysocka
,
+7 authors
G. Trinchieri
European Journal of Immunology
1998
Corpus ID: 29330936
Endotoxin tolerance, the down‐regulation of a subset of endotoxin‐driven responses after an initial exposure to endotoxin, may…
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Highly Cited
1995
Highly Cited
1995
Characterization of the Promoter Region of the Human Transforming Growth Factor-β Type II Receptor Gene *
H. Bae
,
A. Geiser
,
+5 authors
Seong-Jin Kim
Journal of Biological Chemistry
1995
Corpus ID: 35508573
Diminished cellular responsiveness to transforming growth factor-β (TGF-β) is frequently correlated with decreased transcription…
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Highly Cited
1994
Highly Cited
1994
Hepatocyte Growth Factor/Scatter Factor Has Insulinotropic Activity in Human Fetal Pancreatic Cells
T. Otonkoski
,
G. Beattie
,
J. Rubin
,
Ana D. Lopez
,
A. Baird
,
A. Hayek
Diabetes
1994
Corpus ID: 19521840
Fetal mesenchyme-derived factors are likely to play an important role in pancreatic islet development and growth. We have used…
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Highly Cited
1993
Highly Cited
1993
Production of transforming growth factor-beta by Mycobacterium avium-infected human macrophages is associated with unresponsiveness to IFN-gamma.
L. Bermudez
Journal of Immunology
1993
Corpus ID: 43232273
Transforming growth factor-beta 1 (TGF-beta 1) is a potent immunoregulatory molecule. It modulates production of cytokines, such…
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Highly Cited
1993
Highly Cited
1993
Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6.
D. McGee
,
Kenneth W. Beagley
,
W. Aicher
,
Jerry R. McGhee
Journal of Immunology
1993
Corpus ID: 24592361
Intestinal epithelial cells are a potentially important source for a number of cytokines that may modulate the immune response at…
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Highly Cited
1992
Highly Cited
1992
Evidence for transforming growth factor-beta expression in human leptomeningeal cells and transforming growth factor-beta-like activity in human cerebrospinal fluid.
M. Johnson
,
L. Gold
,
H. Moses
Laboratory investigation; a journal of technical…
1992
Corpus ID: 33579861
BACKGROUND Little is known about the factors regulating growth and maintenance of human leptomeningeal cells. The influence of…
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Review
1991
Review
1991
Response of prostate cancer cells to peptide growth factors: transforming growth factor-beta.
G. Wilding
Cancer Surveys
1991
Corpus ID: 36398082
The growth of human prostate cancer and its relationship to the surrounding stroma are controlled by complex mechanisms that are…
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Highly Cited
1984
Highly Cited
1984
Human and bovine milk contain different sets of growth factors.
Y. Shing
,
M. Klagsbrun
Endocrinology
1984
Corpus ID: 8620763
Growth factor activity is present in human milk throughout the lactation period but is in bovine milk only during the colostral…
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