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Transforming Growth Factor beta

Known as: TGFbeta, Milk Growth Factor, Transforming growth factors-beta 
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a… Expand
National Institutes of Health

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31 relations
Cell Differentiation processCell Proliferation Regulatory ProcessExtracellular SpaceGDNF protein, human
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Transforming Growth Factor-β Signaling in Immunity and Cancer.
Transforming growth factor (TGF)-β is a crucial enforcer of immune homeostasis and tolerance, inhibiting the expansion and… Expand
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Review
2018
Review
2018
GDF-9 and BMP-15 direct the follicle symphony
Understanding the physiology underlying the complex dialog between the oocyte and its surrounding somatic cells within the… Expand
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Highly Cited
2007
Highly Cited
2007
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells.
Interleukin 17 (IL-17)-producing CD4(+) helper T cells (T(H)-17 cells) have been linked to host defense and autoimmune diseases… Expand
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Highly Cited
1994
Highly Cited
1994
Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.
Angiotensin II (Ang II) has been implicated in the development of progressive glomerulosclerosis, but the precise mechanism of… Expand
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Review
1990
Review
1990
The transforming growth factor-beta family.
  • J. Massagué
  • Annual review of cell biology
  • 1990
    • Corpus ID: 35109826
 
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Highly Cited
1988
Highly Cited
1988
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium
Transforming growth factor-beta (TGF beta) is produced by most cultured cells in an inactive form. Potential activation… Expand
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Highly Cited
1987
Highly Cited
1987
Accelerated healing of incisional wounds in rats induced by transforming growth factor-beta.
The role of polypeptide growth factors in the processes of inflammation and repair was investigated by analyzing the influence of… Expand
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Highly Cited
1986
Highly Cited
1986
Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.
Transforming growth factor type beta (TGF-beta), when injected subcutaneously in newborn mice, causes formation of granulation… Expand
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Highly Cited
1986
Highly Cited
1986
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
We have examined whether the extracellular matrix is a biochemical target for transforming growth factor-beta (TGFbeta). We find… Expand
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Highly Cited
1983
Highly Cited
1983
Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.
Acidic ethanol extracts of human platelets induced non-neoplastic normal rat kidney fibroblasts to undergo anchorage-independent… Expand
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