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Transforming Growth Factor beta

Known as: TGFbeta, Milk Growth Factor, Transforming growth factors-beta 
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a… 
National Institutes of Health

Related topics

Related topics

31 relations
Cell Differentiation processCell Proliferation Regulatory ProcessExtracellular SpaceGDNF protein, human

Narrower (9)

Vg1 protein, XenopusbetaIG-H3 proteindvr1 protein, zebrafishfugacin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Involvement of Calcineurin in Transforming Growth Factor-β-mediated Regulation of Extracellular Matrix Accumulation*
Calcineurin is a calcium-dependent, serine/threonine phosphatase that functions as a signaling intermediate. In this study, we… 
Highly Cited
1999
Highly Cited
1999
Glial Cell Line-Derived Neurotrophic Factor Rescues Target-Deprived Sympathetic Spinal Cord Neurons But Requires Transforming Growth Factor-β as Cofactor In Vivo
Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor for several populations of CNS and peripheral… 
Highly Cited
1998
Highly Cited
1998
Potent suppression of IL‐12 production from monocytes and dendritic cells during endotoxin tolerance
Endotoxin tolerance, the down‐regulation of a subset of endotoxin‐driven responses after an initial exposure to endotoxin, may… 
Highly Cited
1995
Highly Cited
1995
Characterization of the Promoter Region of the Human Transforming Growth Factor-β Type II Receptor Gene *
Diminished cellular responsiveness to transforming growth factor-β (TGF-β) is frequently correlated with decreased transcription… 
Highly Cited
1994
Highly Cited
1994
Hepatocyte Growth Factor/Scatter Factor Has Insulinotropic Activity in Human Fetal Pancreatic Cells
Fetal mesenchyme-derived factors are likely to play an important role in pancreatic islet development and growth. We have used… 
Highly Cited
1993
Highly Cited
1993
Production of transforming growth factor-beta by Mycobacterium avium-infected human macrophages is associated with unresponsiveness to IFN-gamma.
Transforming growth factor-beta 1 (TGF-beta 1) is a potent immunoregulatory molecule. It modulates production of cytokines, such… 
Highly Cited
1993
Highly Cited
1993
Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6.
Intestinal epithelial cells are a potentially important source for a number of cytokines that may modulate the immune response at… 
Highly Cited
1992
Highly Cited
1992
Evidence for transforming growth factor-beta expression in human leptomeningeal cells and transforming growth factor-beta-like activity in human cerebrospinal fluid.
BACKGROUND Little is known about the factors regulating growth and maintenance of human leptomeningeal cells. The influence of… 
Review
1991
Review
1991
Response of prostate cancer cells to peptide growth factors: transforming growth factor-beta.
The growth of human prostate cancer and its relationship to the surrounding stroma are controlled by complex mechanisms that are… 
Highly Cited
1984
Highly Cited
1984
Human and bovine milk contain different sets of growth factors.
Growth factor activity is present in human milk throughout the lactation period but is in bovine milk only during the colostral… 
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