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betaIG-H3 protein

Known as: beta IG-H3 protein, BIGH3 protein, transforming growth factor-beta induced protein 
 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Extracellular Matrix ProteinsTransforming Growth Factor beta
TGFBI gene

Narrower (2)

TGFBI protein, humantgfbi protein, zebrafish

Papers overview

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Highly Cited
2008
Highly Cited
2008
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation.
Metastasis, the major cause of cancer death, is a multistep process that requires interactions between cancer cells and stromal… Expand
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2008
2008
Keratoepithelin reverts the suppression of tissue factor pathway inhibitor 2 by MYCN in human neuroblastoma: a mechanism to inhibit invasion.
Neuroblastoma is the most frequent solid malignancy of children. The most reliable prognostic factor in neuroblastoma is the… Expand
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2006
2006
Systemic investigation of keratoepithelin deposits in TGFBI/BIGH3-related corneal dystrophy.
PURPOSE To investigate the location and tissue-specificity of the pathologic keratoepithelin (KE) deposition in a patient with a… Expand
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2006
2006
Keratoepithelin suppresses the progression of experimental human neuroblastomas.
Neuroblastoma is the most common extracranial childhood tumor. High expression of activin A is associated with a favorable… Expand
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2002
2002
Induction and expression of betaig-h3 in pancreatic cancer cells.
betaig-h3 (TGFBI, keratoepithelin) was first identified as a transforming growth factor-beta1 (TGF-beta1)-inducible gene in a… Expand
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Highly Cited
2000
Highly Cited
2000
Amyloid and non-amyloid forms of 5q31-linked corneal dystrophy resulting from kerato-epithelin mutations at Arg-124 are associated with abnormal turnover of the protein.
Mutations in kerato-epithelin are responsible for a group of hereditary cornea-specific deposition diseases, 5q31-linked corneal… Expand
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1999
1999
On the role of kerato-epithelin in the pathogenesis of 5q31-linked corneal dystrophies.
PURPOSE Recently, the authors identified a gene, BIGH3, in which different mutations cause a group of hereditary corneal… Expand
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1998
1998
Two distinct kerato-epithelin mutations in Reis-Bücklers corneal dystrophy.
PURPOSE Two patients were diagnosed with Reis-Bücklers corneal dystrophy (RBCD), although the pattern and severity of corneal… Expand
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1998
1998
A common beta ig-h3 gene mutation (delta f540) in a large cohort of Sardinian Reis Bücklers corneal dystrophy patients. Mutations in brief no. 180. Online.
Reis-Bücklers' corneal dystrophy (RBCD) is a relatively rare autosomal dominant disease originating in the Bowman's membrane… Expand
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1998
1998
Lattice corneal dystrophy type 1 in a Canadian kindred is associated with the Arg124 --> Cys mutation in the kerato-epithelin gene. sgupta@ogh.on.ca.
PURPOSE To identify the mutation responsible for lattice corneal dystrophy type 1 in an extended Canadian kindred. METHODS A… Expand
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