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BMP2 protein, human

Known as: Bone Morphogenetic Protein 2, BMP-2 protein, human, BMP-2 
Bone morphogenetic protein 2 (396 aa, ~45 kDa) is encoded by the human BMP2 gene. This protein plays a role in cartilage and bone formation.
National Institutes of Health

Related topics

Related topics

29 relations
ALK PathwayBMP2 geneBone Morphogenetic Protein GeneBrain

Broader (1)

bone morphogenetic protein 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
LncRNA MSC-AS1 promotes osteogenic differentiation and alleviates osteoporosis through sponging microRNA-140-5p to upregulate BMP2.
Highly Cited
2010
Highly Cited
2010
Tensile Strain as a Regulator of Mesenchymal Stem Cell Osteogenesis
A role for mechanical stimulation in the control of cell fate has been proposed and mechanical conditioning of mesenchymal stem… 
Review
2009
Review
2009
BMP2 signaling in bone development and repair.
Highly Cited
2007
Highly Cited
2007
Murine and Chicken Chondrocytes Regulate Osteoclastogenesis by Producing RANKL in Response to BMP2
Chondrocytes express RANKL, but their role in osteoclastogenesis is not clear. We report that hypertrophic chondrocytes induce… 
Highly Cited
2006
Highly Cited
2006
BMP is an important regulator of proepicardial identity in the chick embryo.
Highly Cited
2005
Highly Cited
2005
Combined effects of TGFβ1 and BMP2 in serum-free chondrogenic differentiation of mesenchymal stem cells induced hyaline-like cartilage formation
This study investigated the effects of TGFβ1, BMP2 or a combination of both on the chondrogenic differentiation of mesenchymal… 
Highly Cited
2005
Highly Cited
2005
Runx2 regulates FGF2‐induced Bmp2 expression during cranial bone development
Calvarial bone is formed by the intramembranous bone‐forming process, which involves many signaling molecules. The constitutive… 
Highly Cited
2004
Highly Cited
2004
Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia
Biochemical experiments have shown that Smad6 and Smad ubiquitin regulatory factor 1 (Smurf1) block the signal transduction of… 
Highly Cited
2003
Highly Cited
2003
BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels.
The tumour suppressor gene PTEN encodes a dual-specificity phosphatase that recognizes protein and phosphatidylinositiol… 
Highly Cited
2001
Highly Cited
2001
Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.
The primordial germ cells (PGCs) of the mouse are derived from proximal epiblast cells that are adjacent to the extraembryonic… 
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