Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells

@inproceedings{Zhang2014BoneMP,
  title={Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells},
  author={Yunyuan Zhang and Xian Chen and Min Qiao and Bing-qiang Zhang and Ning Wang and Zhonglin Zhang and Zhan Liao and Liyi Zeng and Youlin Deng and Fang Deng and Junhui Zhang and Liang-jun Yin and Wei Liu and Qian Zhang and Zhengjian Yan and Jixing Ye and Zhongliang Wang and Lan Zhou and Hue H. Luu and Rex C. Haydon and Tong-Chuan He and Hongyu Zhang},
  booktitle={Oncology reports},
  year={2014}
}
  • Yunyuan Zhang, Xian Chen, +19 authors Hongyu Zhang
  • Published in Oncology reports 2014
  • Biology, Medicine
  • Colorectal cancer (CRC) is one of the most deadly cancers worldwide. Significant progress has been made in understanding the molecular pathogenesis of CRC, which has led to successful early diagnosis, surgical intervention and combination chemotherapy. However, limited therapeutic options are available for metastatic and/or drug-resistant CRC. While the aberrantly activated Wnt/β-catenin pathway plays a critical initiating role in CRC development, disruption of the bone morphogenetic protein… CONTINUE READING

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