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OBJECTIVES Hypervitaminosis A and alcoholism can result in a low mineral density and compromised regenerative capacity of bone, thus delaying implant osteointegration. The inhibitory effect of all-trans retinoic acid on osteoblastogenesis is considered to be one of the mechanisms. We hypothesized that heterodimeric bone morphogenetic protein-2/7 could(More)
Most materials used clinically for filling critical-sized bone defects (CSBD), such as deproteinized bovine bone (DBB), lack osteoinductivity so that their therapeutic effects are far from satisfactory. The effect of bone morphogenic protein 2 (BMP2)-coprecipitated biomimetic calcium phosphate granules (BMP2-cop.BioCaP) on osteoinduction of DBB graft(s)(More)
No part of this book may be reproduced, stored in a retrievable system, or transmitted in any form or by any means, mechanical, photocopying , recording or otherwise, without the prior written permission of the holder of copyright. Dedicated to my wife Qian Lu to my parents Publications 1. Tie Liu, Bing Xia, Zhiyuan Gu. Inferior alveolar canal course: a(More)
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