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TPO protein, human

Known as: thyroid peroxidase protein, human, Tyrosine Iodinase, microsomal autoantigen, human 
Thyroid peroxidase (933 aa, ~103 kDa) is encoded by the human TPO gene. This protein plays a role in thyroid hormone synthesis.
National Institutes of Health

Related topics

Related topics

17 relations
AnabolismEGF-Like DomainEnzyme GeneGlycoproteins

Broader (3)

AutoantigensIodide PeroxidaseIron-Binding Proteins

Papers overview

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2014
2014
Melatonin modulates microsomal PGE synthase 1 and NF‐E2‐related factor‐2‐regulated antioxidant enzyme expression in LPS‐induced murine peritoneal macrophages
Increasing evidence demonstrates that melatonin regulates inflammatory and immune processes acting as both an activator and… 
2011
2011
2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes.
Developmental exposure to multiple ortho-substituted polychlorinated biphenyls (PCBs) causes adverse neurodevelopmental outcomes… 
Highly Cited
1996
Highly Cited
1996
Bromoperoxidase and iodoperoxidase enzymes and production of halogenated methanes in marine diatom cultures
Halogenated methanes produced in the oceans are important as carriers of chlorine, bromine, and iodine into the atmosphere. There… 
1993
1993
Identification and characterization of two enzymes involved in the intracellular metabolism of cobalamin. Cyanocobalamin beta-ligand transferase and microsomal cob(III)alamin reductase.
Highly Cited
1991
Highly Cited
1991
Variable product specificity of microsomal dehydrodolichyl diphosphate synthase from rat liver.
1980
1980
Role of hydroxyl radicals in the iron-ethylenediaminetetraacetic acid mediated stimulation of microsomal oxidation of ethanol.
The microsomal oxidation of ethanol or 1-butanol was increased by ferrous ammonium sulfate-ethylenediaminetetraacetic acid (1:2… 
1972
1972
Abnormal thyroid peroxidase causing iodide organification defect.
The spectrum of familial goiter due to iodide organification defect includes goitrous cretins, Pendred's syndrome, and goiter… 
Highly Cited
1970
Highly Cited
1970
Studies on the synthesis and transport of albumin in microsomal subfractions from rat liver.
1970
1970
Alteration of Microsomal Biotransformation in the Liver in Cholestasis 1
Summary In cholestasis, 4 days after bile duct ligation, the activity of aminopyrine demethylase was greatly decreased, while the… 
Highly Cited
1966
Highly Cited
1966
Enzymatic iodination of tyrosine and thyroglobulin with chloroperoxidase.
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