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Iodide Peroxidase

Known as: tpos, Deiodinase, Iodotyrosine, Deiodase, Iodotyrosine 
A hemeprotein that catalyzes the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly… 
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (5)

Deficiency of iodide peroxidase (disorder)TPO protein, humanThyroid Dyshormonogenesis 4iodothyronine deiodinase type I

Broader (2)

IYD genePeroxidases
In BloodIodothyronine 5'-DeiodinaseIodothyronine DeiodinasePeroxidase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Thyroid disruption in walleye (Sander vitreus) exposed to environmental contaminants: cloning and use of iodothyronine deiodinases as molecular biomarkers.
Highly Cited
2006
Highly Cited
2006
Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice.
The thyroid gland is rich in selenium (Se) and expresses a variety of selenoproteins that are involved in antioxidative defense… 
Highly Cited
1999
Highly Cited
1999
Purification, Redox Sensitivity, and RNA Binding Properties of SECIS-binding Protein 2, a Protein Involved in Selenoprotein Biosynthesis*
In mammalian selenoprotein mRNAs, the highly structured 3′ UTR contains selenocysteine insertion sequence (SECIS) elements that… 
Highly Cited
1998
Highly Cited
1998
Thrombopoietin promotes the survival of murine hematopoietic long-term reconstituting cells: comparison with the effects of FLT3/FLK-2 ligand and interleukin-6.
The effects of thrombopoietin (TPO; c-mpl ligand), FLT3/FLK-2 ligand (FL), and interleukin-6 (IL-6) on the survival of murine… 
Highly Cited
1995
Highly Cited
1995
Cloning and Functional Characterization of Human Selenophosphate Synthetase, an Essential Component of Selenoprotein Synthesis (*)
Selenocysteine is co-translationally incorporated into prokaryotic and eukaryotic selenoproteins at in-frame UGA codons. However… 
Highly Cited
1995
Highly Cited
1995
Longitudinal study of antibodies against thyroid in patients undergoing interferon-alpha therapy for HCV chronic hepatitis.
Seventy-five patients (50 M, 25 F), affected by chronic hepatitis caused by hepatitis C virus (HCV), without clinically overt… 
Highly Cited
1994
Highly Cited
1994
Mechanism-based inactivation of lactoperoxidase and thyroid peroxidase by resorcinol derivatives.
Humans are exposed to resorcinol derivatives in the environment through ground water, foods, food additives, drugs, and hair dyes… 
Highly Cited
1982
Highly Cited
1982
Mechanism of inactivation of thyroid peroxidase by thioureylene drugs.
Highly Cited
1978
Highly Cited
1978
Thyroxine 5'-deiodinase activity of rat kidney: observations on activation by thiols and inhibition by propylthiouracil.
Enzymatic 5'-deiodination of T4 in various tissues is known to be stimulated by thiols and inhibited by propylthiouracil (PTU… 
Review
1970
Review
1970
Thyroid peroxidase and thyroxine biosynthesis.
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