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Iodide Peroxidase
Known as:
tpos
, Deiodinase, Iodotyrosine
, Deiodase, Iodotyrosine
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A hemeprotein that catalyzes the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly…
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National Institutes of Health
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Related topics
Related topics
24 relations
Narrower (5)
Deficiency of iodide peroxidase (disorder)
TPO protein, human
Thyroid Dyshormonogenesis 4
iodothyronine deiodinase type I
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Broader (2)
IYD gene
Peroxidases
In Blood
Iodothyronine 5'-Deiodinase
Iodothyronine Deiodinase
Peroxidase
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8.
Marija Trajkovic
,
T. Visser
,
+6 authors
H. Heuer
Journal of Clinical Investigation
2007
Corpus ID: 22149330
In humans, inactivating mutations in the gene of the thyroid hormone transporter monocarboxylate transporter 8 (MCT8; SLC16A2…
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Review
2002
Review
2002
Action of thyroid hormone in brain
J. Bernal
Journal of Endocrinological Investigation
2002
Corpus ID: 3252861
Among the most critical actions of thyroid hormone in man and other mammals are those exerted on brain development. Severe…
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Highly Cited
2000
Highly Cited
2000
Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas.
Stephen A. Huang
,
H. Tu
,
+5 authors
P. Larsen
New England Journal of Medicine
2000
Corpus ID: 38728448
Hemangiomas are the most common tumors of infancy, with a prevalence of 5 to 10 percent among one-year-olds. They are…
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Review
1999
Review
1999
Local activation and inactivation of thyroid hormones: the deiodinase family
J. Köhrle
Molecular and Cellular Endocrinology
1999
Corpus ID: 11333443
Review
1997
Review
1997
The deiodinase family of selenoproteins.
D. L. Germain
,
V. Galton
Thyroid
1997
Corpus ID: 13523855
The realization some forty years ago that several iodothyronine compounds are present in the circulation suggested that…
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Highly Cited
1997
Highly Cited
1997
Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone.
H. Tu
,
Sung-Woo Kim
,
+4 authors
R. Lechan
Endocrinology
1997
Corpus ID: 45227016
To identify the specific locations of type 2 deiodinase (D2) messenger RNA (mRNA) in the hypothalamus and pituitary gland and…
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Highly Cited
1997
Highly Cited
1997
The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain.
A. Guadaño-Ferraz
,
M. Obregon
,
D. L. Germain
,
J. Bernal
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 23612531
Thyroid hormone plays an essential role in mammalian brain maturation and function, in large part by regulating the expression of…
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Highly Cited
1995
Highly Cited
1995
Tissue-specific regulation of selenoenzyme gene expression during selenium deficiency in rats.
Giovanna Bermano
,
F. Nicol
,
+4 authors
John E. Hesketh
Biochemical Journal
1995
Corpus ID: 25380409
Regulation of synthesis of the selenoenzymes cytosolic glutathione peroxidase (GSH-Px), phospholipid hydroperoxide glutathione…
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Highly Cited
1983
Highly Cited
1983
Adrenergic activation of triiodothyronine production in brown adipose tissue
J. E. Silva
,
P. Larsen
Nature
1983
Corpus ID: 4360228
There are several mechanisms by which homeothermic animals increase heat production, including shivering, sympathetic nervous…
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Highly Cited
1978
Highly Cited
1978
Iodothyronine metabolism in rat liver homogenates.
M. Kaplan
,
R. Utiger
Journal of Clinical Investigation
1978
Corpus ID: 9514068
To investigate mechanisms of extrathyroidal thyroid hormone metabolism, conversion of thyroxine (T(4)) to 3,5,3'-triiodothyronine…
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