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Peroxidase

Known as: Myeloperoxidase, Peroxidase [Chemical/Ingredient], MPO 
A hemeprotein from leukocytes. Deficiency of this enzyme leads to a hereditary disorder coupled with disseminated moniliasis. It catalyzes the… 
National Institutes of Health

Related topics

Related topics

50 relations
Antimicrobial EffectBAS1 protein, ArabidopsisCells.myeloperoxidase:PrThr:Pt:Body fld:OrdCytochrome c Peroxidase

Broader (1)

Oxidoreductase

Narrower (1)

guaiacol peroxidase

Papers overview

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Highly Cited
2009
Highly Cited
2009
The extracellular release of granulocyte collagenase and elastase during phagocytosis and inflammatory processes.
Human granulocytes release 25-30% of the granular neutral proteases, collagenase and elastase, to the exterior of the cell during… 
Highly Cited
2007
Highly Cited
2007
ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
PURPOSE To elucidate the role of ST2, a member of the TLR/IL-1R (TIR) superfamily, in protecting against Pseudomonas aeruginosa… 
Highly Cited
2000
Highly Cited
2000
Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein.
Activated phagocytes produce the highly reactive oxidant hypochlorous acid (HOCl) via the myeloperoxidase-catalysed reaction of… 
Highly Cited
1990
Highly Cited
1990
Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system.
Neutrophil myeloperoxidase, hydrogen peroxide, and chloride constitute a potent antimicrobial system with multiple effects on… 
Highly Cited
1986
Highly Cited
1986
Analysis of the peptide subunits of human neutrophil myeloperoxidase.
Myeloperoxidase is a cationic protein present in the azurophilic granules of human neutrophils and constitutes 2% to 5% of… 
Highly Cited
1985
Highly Cited
1985
Antiarthritic drugs containing thiol groups scavenge hypochlorite and inhibit its formation by myeloperoxidase from human leukocytes. A therapeutic mechanism of these drugs in rheumatoid arthritis?
We investigated the effect of antiarthritic drugs containing thiol groups, such as D-penicillamine, tiopronin (N-[2… 
Highly Cited
1984
Highly Cited
1984
Structural analysis of myeloperoxidase by resonance Raman spectroscopy.
Soret excitation of canine myeloperoxidase (MPO) gives rise to a complex resonance Raman (RR) spectrum characterized by multiple… 
Highly Cited
1975
Highly Cited
1975
Effects of anaerobiosis and inhibitors on O2-production by human granulocytes.
A study was carried out on the effect of a number of inhibitors as well as of anaerobiosis on the production of superoxide (O2… 
Highly Cited
1974
Highly Cited
1974
Oxidative Peptide Cleavage and Decarboxylation by the MPO-H2O2-Cl− Antimicrobial System
The antimicrobial activities of the myeloperoxidase-H2O2-halide system have received considerable attention recently. The precise… 
Highly Cited
1972
Highly Cited
1972
Refractory megaloblastic anemia with myeloperoxidase-deficient neutrophils.
Abstract The enzyme myeloperoxidase contributes to the ability of human leukocytes to kill fungi and bacteria. We studied a 61… 
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