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TOR complex 2
Known as:
mTOR Complex 2
, Target of Rapamycin Complex 2
, TORC2
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A protein complex that is involved in both serine/threonine phosphorylation and cytoskeleton remodeling in response to cellular stress.
National Institutes of Health
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Related topics
Related topics
7 relations
DEP Domain-Containing mTOR-Interacting Protein
FRAP1 protein, human
MTOR gene
Serine/Threonine Phosphorylation
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Broader (2)
FKBP12-rapamycin associated protein
Multiprotein Complexes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Understanding the role of mTORC1 and mTORC2 in embryonic and adult myogenesis
Nathalie Rion
2017
Corpus ID: 90046862
Myogenesis describes the formation of skeletal muscle fibers during embryogenesis and their regeneration of injury in the adult…
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2015
2015
TORC 2 and eisosomes are spatially interdependent , requiring optimal level of phosphatidylinositol 4 , 5-bisphosphate for their
Katelyn Bartlett
,
Shiva Kumar
,
+4 authors
Kyoungtae Kim
2015
Corpus ID: 165160270
The elucidation of the organization and maintenance of the plasma membrane has been sought due to its numerous roles in cellular…
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2014
2014
PI 3 k / mTOR pathway inhibition uncovers heterogenous Akt isoform activation associated with PTEN mutation status in breast cancer cell lines
Suzi Fei
,
Nicholas Wang
,
+9 authors
J. Muschler
2014
Corpus ID: 53345955
Epidemiological studies have identified early age pregnancy as protective against a woman’s life-long breast cancer risk…
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2014
2014
Cancer Biology and Signal Transduction Genetic and Pharmacologic Evidence That mTOR Targeting Outweighs mTORC 1 Inhibition as an Antimyeloma Strategy
X. Chen
,
Elena Díaz-Rodríguez
,
+6 authors
A. Pandiella
2014
Corpus ID: 11461522
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates cell growth, proliferation, metabolism, and…
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2013
2013
Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC 2 / Akt pathway
Rajalaxmi Natarajan
,
Deepti Trivedi-Vyas
,
Yogesh P. Wairkar
2013
Corpus ID: 189799299
Mutations in the tuberous sclerosis complex (TSC) are associated with various forms of neurodevelopmental disorders, including…
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2013
2013
LKB1-AMPK-SIK2-CRTC2 Pathway in Beta Cells
Accalia Fu
2013
Corpus ID: 99794639
CREB is a cyclic AMPand calcium-responsive transcriptional activator that is required for islet beta cell proliferation and…
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2012
2012
The Relation between Resveratrol, Sirt1, mTOR and Autophagy
C. Erdogan
,
Hai-Dang-Wu Le
2012
Corpus ID: 92630003
Autophagy is an intracellular degradation system of proteins and organelles. It has several roles in the cell under different…
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2012
2012
Regulación de la homeostasis iónica por los complejos TORC1 y TORC2.
Marchena López
2012
Corpus ID: 82575800
2011
2011
Abstract 4486: INK128, a novel TORC1/2 inhibitor with potent oral antitumor activity in preclinical models of renal cancer
Shun-You Wang
,
Katti A. Jessen
,
+13 authors
Yi Liu
2011
Corpus ID: 71239458
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Objective: Preclinical characterization and evaluation…
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2011
2011
Adrenergic Regulation of the Distribution of Transducer of Regulated cAMP-Response Element-Binding Protein ( TORC 2 ) in Rat
R. Kanyo
,
N. Amyotte
,
J. McTague
,
C. Chik
,
A. Ho
2011
Corpus ID: 20849629
Transducers of regulated cAMP-response element-binding protein (CREB) activity (TORC) are coactivators that can increase CREB…
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