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TOR complex 2

Known as: mTOR Complex 2, Target of Rapamycin Complex 2, TORC2 
A protein complex that is involved in both serine/threonine phosphorylation and cytoskeleton remodeling in response to cellular stress.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The TOR kinase, which is present in the functionally distinct complexes TORC1 and TORC2, is essential for growth but associated… Expand
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Highly Cited
2009
Highly Cited
2009
Effector T cell differentiation requires the simultaneous integration of multiple, and sometimes opposing, cytokine signals. We… Expand
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Review
2009
Review
2009
Research on TOR has grown exponentially during the last decade, generating a complex model of the TOR signaling network… Expand
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Highly Cited
2008
Highly Cited
2008
SGK1 (serum- and glucocorticoid-induced protein kinase 1) is a member of the AGC (protein kinase A/protein kinase G/protein… Expand
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Highly Cited
2008
Highly Cited
2008
Protein kinase C (PKC) is involved in a wide array of cellular processes such as cell proliferation, differentiation and… Expand
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Highly Cited
2006
Highly Cited
2006
Mammalian target of rapamycin (mTOR) controls cell growth and proliferation via the raptor-mTOR (TORC1) and rictor-mTOR (TORC2… Expand
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Highly Cited
2005
Highly Cited
2005
The Peutz-Jegher syndrome tumor-suppressor gene encodes a protein-threonine kinase, LKB1, which phosphorylates and activates AMPK… Expand
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Highly Cited
2005
Highly Cited
2005
Glucose homeostasis is regulated systemically by hormones such as insulin and glucagon, and at the cellular level by energy… Expand
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Highly Cited
2004
Highly Cited
2004
The target of rapamycin (TOR) is a highly conserved protein kinase and a central controller of cell growth. In budding yeast, TOR… Expand
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Highly Cited
2002
Highly Cited
2002
The target of rapamycin (TOR) proteins in Saccharomyces cerevisiae, TOR1 and TOR2, redundantly regulate growth in a rapamycin… Expand
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