FRAP1 protein, human

Known as: RAFT1 protein, human, FKBP12-Rapamycin Complex-Associated Protein, FKBP-Rapamycin Associated Protein 
A protein that helps control several cell functions, including cell division and survival, and binds to rapamycin and other drugs. Mammalian target… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The mechanistic target of rapamycin (mTOR) coordinates eukaryotic cell growth and metabolism with environmental inputs, including… (More)
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Highly Cited
2011
Highly Cited
2011
Autophagy is a process by which components of the cell are degraded to maintain essential activity and viability in response to… (More)
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Highly Cited
2010
Highly Cited
2010
The rapid antidepressant response after ketamine administration in treatment-resistant depressed patients suggests a possible new… (More)
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Highly Cited
2009
Highly Cited
2009
The mammalian target of rapamycin (mTOR) kinase is the catalytic subunit of two functionally distinct complexes, mTORC1 and… (More)
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Highly Cited
2009
Highly Cited
2009
Autophagy, the starvation-induced degradation of bulky cytosolic components, is up-regulated in mammalian cells when nutrient… (More)
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Highly Cited
2006
Highly Cited
2006
Stimulation of the insulin and insulin-like growth factor I (IGF-I) receptor activates the phosphoinositide-3-kinase/Akt/mTOR… (More)
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Highly Cited
2005
Highly Cited
2005
Deregulation of Akt/protein kinase B (PKB) is implicated in the pathogenesis of cancer and diabetes. Akt/PKB activation requires… (More)
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Highly Cited
2002
Highly Cited
2002
Tuberous sclerosis (TSC) is an autosomal dominant disorder characterized by the formation of hamartomas in a wide range of human… (More)
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Highly Cited
2001
Highly Cited
2001
Skeletal muscles adapt to changes in their workload by regulating fibre size by unknown mechanisms. The roles of two signalling… (More)
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Highly Cited
2001
Highly Cited
2001
Skeletal muscle is composed of multinucleated fibres, formed after the differentiation and fusion of myoblast precursors… (More)
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