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FRAP1 protein, human

Known as: RAFT1 protein, human, FKBP12-Rapamycin Complex-Associated Protein, FKBP-Rapamycin Associated Protein 
A protein that helps control several cell functions, including cell division and survival, and binds to rapamycin and other drugs. Mammalian target… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling is one of the most important… Expand
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Review
2019
Review
2019
The highly conserved protein kinase mechanistic target of rapamycin (mTOR; originally known as mammalian target of rapamycin) is… Expand
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Review
2019
Review
2019
ABSTRACT Mitophagy is a vital form of autophagy for selective removal of dysfunctional or redundant mitochondria. Accumulating… Expand
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Review
2019
Review
2019
Autophagy is a preserved cytoplasmic self‐degradation process and endorses recycling of intracellular constituents into… Expand
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Review
2018
Review
2018
Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the United States and many developed nations… Expand
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Highly Cited
2011
Highly Cited
2011
Autophagy is a process by which components of the cell are degraded to maintain essential activity and viability in response to… Expand
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Highly Cited
2006
Highly Cited
2006
Stimulation of the insulin and insulin-like growth factor I (IGF-I) receptor activates the phosphoinositide-3-kinase/Akt/mTOR… Expand
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Highly Cited
2005
Highly Cited
2005
Deregulation of Akt/protein kinase B (PKB) is implicated in the pathogenesis of cancer and diabetes. Akt/PKB activation requires… Expand
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Highly Cited
2002
Highly Cited
2002
Tuberous sclerosis (TSC) is an autosomal dominant disorder characterized by the formation of hamartomas in a wide range of human… Expand
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Highly Cited
2002
Highly Cited
2002
mTOR/RAFT1/FRAP is the target of the immunosuppressive drug rapamycin and the central component of a nutrient- and hormone… Expand
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