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FKBP12-rapamycin associated protein
Known as:
mTOR Serine Threonine Kinases
, Associated Protein, FKBP12-Rapamycin
, Protein, mTOR
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A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due…
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National Institutes of Health
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Related topics
Related topics
14 relations
Narrower (3)
FRAP1 protein, human
TOR complex 2
mechanistic target of rapamycin complex 1
In Blood
MTOR gene
Process of secretion
RNA, Messenger
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Broader (1)
Protein Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae.
Sofia Aronova
,
K. Wedaman
,
Scott D. Anderson
,
J. Yates
,
T. Powers
Molecular Biology of the Cell
2007
Corpus ID: 10022098
The TOR kinases are regulators of growth in eukaryotic cells that assemble into two distinct protein complexes, TORC1 and TORC2…
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Highly Cited
2007
Highly Cited
2007
Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines
L. Toral‐Barza
,
Wei-Guo Zhang
,
+14 authors
Ker Yu
Molecular Cancer Therapeutics
2007
Corpus ID: 21603479
The serine/threonine kinase AKT/PKB plays a critical role in cancer and represents a rational target for therapy. Although…
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2007
2007
Distant N- and C-terminal Domains Are Required for Intrinsic Kinase Activity of SMG-1, a Critical Component of Nonsense-mediated mRNA Decay*
Tomoko Morita
,
A. Yamashita
,
Isao Kashima
,
K. Ogata
,
S. Ishiura
,
S. Ohno
Journal of Biological Chemistry
2007
Corpus ID: 5964414
Phosphatidylinositol 3-kinase-related kinases (PIKKs) consisting of SMG-1, ATM, ATR, DNA-PKcs, and mTOR are a family of proteins…
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Highly Cited
2002
Highly Cited
2002
The Flavoprotein MrsD Catalyzes the Oxidative Decarboxylation Reaction Involved in Formation of the Peptidoglycan Biosynthesis Inhibitor Mersacidin
Florian Majer
,
D. Schmid
,
K. Altena
,
G. Bierbaum
,
T. Kupke
Journal of Bacteriology
2002
Corpus ID: 13278721
ABSTRACT The lantibiotic mersacidin inhibits peptidoglycan biosynthesis by binding to the peptidoglycan precursor lipid II…
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Highly Cited
1998
Highly Cited
1998
Occurrence of an Unusual Phospholipid, Phosphatidyl-l-threonine, in Cultured Hippocampal Neurons
J. Mitoma
,
T. Kasama
,
S. Furuya
,
Y. Hirabayashi
Journal of Biological Chemistry
1998
Corpus ID: 40376948
We have recently reported thatl-serine released from astroglial cells supports the survival and neuritogenesis of hippocampal…
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Highly Cited
1990
Highly Cited
1990
Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation.
J. Countaway
,
Patricia A. McQuilkin
,
Núria Gironès
,
Roger J. Davis
Journal of Biological Chemistry
1990
Corpus ID: 376237
Highly Cited
1990
Highly Cited
1990
One amino acid change produces a high affinity cGMP-binding site in cAMP-dependent protein kinase.
J. Shabb
,
L. Ng
,
J. Corbin
Journal of Biological Chemistry
1990
Corpus ID: 43844355
Highly Cited
1978
Highly Cited
1978
Baclofen: effects on amino acid release.
S. J. Potashner
Canadian Journal of Physiology and Pharmacology
1978
Corpus ID: 42504500
This study investigated the effects of the antispastic drug β-(p-chlorophenyl)-γ-amino-butyric acid (Baclofen) on the release of…
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1977
1977
Hydrolytic action of aminoacyl-tRNA synthetases from baker's yeast. "Chemical proofreading" of Thr-tRNA Val by valyl-tRNA synthetase studied with modified tRNA Val and amino acid analogues.
G. Igloi
,
F. Von der Haar
,
F. Cramer
Biochemistry
1977
Corpus ID: 33394900
The properties of native and of two modified tRNA Val species in the correction of misactivated threonine by valyl-tRNA…
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1954
1954
C-Terminal groups in myosin, tropomyosin and actin.
R. H. Locker
Biochimica et Biophysica Acta
1954
Corpus ID: 26481757
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