mechanistic target of rapamycin complex 1

Known as: TORC1, Target of Rapamycin Complex 1, mTORC1 
A protein complex that is involved in the both serine/threonine phosphorylation and the regulation of protein synthesis in response to cellular… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
02040608020052017

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2015
2015
Interconversion of white and brown adipocytes occurs between anabolic and catabolic states. The molecular mechanism regulating… (More)
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2014
2014
The mechanistic target of rapamycin (mTOR) exists in two complexes that regulate diverse cellular processes. mTOR complex 1… (More)
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2014
2014
The mechanistic target of rapamycin (mTOR) is activated in CD4(-)CD8(-) double-negative (DN) T cells and its blockade is… (More)
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2014
2014
The mechanisms that control invariant natural killer T (iNKT)-cell development and function are still poorly understood. The… (More)
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Highly Cited
2012
Highly Cited
2012
The mTOR complex 1 (mTORC1) kinase nucleates a pathway that promotes cell growth and proliferation and is the target of rapamycin… (More)
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Highly Cited
2012
Highly Cited
2012
The lysosome plays a key role in cellular homeostasis by controlling both cellular clearance and energy production to respond to… (More)
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Highly Cited
2011
Highly Cited
2011
The nutrient- and growth factor-responsive kinase mTOR complex 1 (mTORC1) regulates many processes that control growth, including… (More)
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Highly Cited
2011
Highly Cited
2011
The mTOR complex 1 (mTORC1) protein kinase is a master growth regulator that is stimulated by amino acids. Amino acids activate… (More)
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Highly Cited
2009
Highly Cited
2009
The mammalian target of rapamycin (mTOR) is centrally involved in cell growth, metabolism, and angiogenesis. While showing… (More)
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Highly Cited
2008
Highly Cited
2008
The mammalian target of rapamycin (mTOR) kinase is a key regulator of several cellular functions, including cell growth and… (More)
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