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Multiprotein Complexes

Known as: Macromolecular Protein Complexes, Multiprotein Complexes [Chemical/Ingredient], Protein Complexes, Macromolecular 
Macromolecular complexes formed from the association of defined protein subunits.
National Institutes of Health

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COP9 signalosome complexTOR complex 2condensin complexesmechanistic target of rapamycin complex 1
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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2014
2014
Identifying nuclear protein-protein interactions using GFP affinity purification and SILAC-based quantitative mass spectrometry.
Many cellular proteins assemble into macromolecular protein complexes. Therefore, identifying protein-protein interactions (PPIs… 
Review
2013
Review
2013
Bringing single-molecule spectroscopy to macromolecular protein complexes.
Review
2012
Review
2012
Coarse-graining of multiprotein assemblies.
Highly Cited
2012
Highly Cited
2012
Bound cations significantly stabilize the structure of multiprotein complexes in the gas phase.
Mass spectrometry (MS) has revealed the composition, stoichiometry, connectivity, and dynamics of many multiprotein complexes… 
2009
2009
Proteomic analyses of native brain KV4.2 channel complexes
Somatodendritic A-type (IA) voltage-gated K+ (KV) channels are key regulators of neuronal excitability, functioning to control… 
Highly Cited
2007
Highly Cited
2007
A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes.
Quantitative description of protein interactions is crucial to understand and model molecular systems regulating various cellular… 
2006
2006
Sequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation.
In human cells, estrogenic signals induce cyclical association and dissociation of specific proteins with the DNA in order to… 
Highly Cited
2003
Highly Cited
2003
Multidimensional nano-HPLC for analysis of protein complexes
Highly Cited
1995
Highly Cited
1995
Self-association of N-Syndecan (Syndecan-3) Core Protein Is Mediated by a Novel Structural Motif in the Transmembrane Domain and Ectodomain Flanking Region (*)
We expressed domains of the core protein of the transmembrane heparan sulfate proteoglycan N-syndecan (syndecan-3) either… 
Highly Cited
1993
Highly Cited
1993
In vitro assembly of multiprotein complexes containing alpha, beta, and gamma tubulin, heat shock protein HSP70, and elongation factor 1 alpha.
We have isolated two sets of multiprotein complexes from supernatants from high-speed centrifugation of nocodazole-arrested CHO… 
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