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MTOR gene

Known as: Mechanistic Target of Rapamycin (Serine/Threonine Kinase) Gene, rapamycin and FKBP12 target 1, rapamycin associated protein FRAP2 
This gene plays a role in apoptosis, cell growth, differentiation and proliferation.
National Institutes of Health

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Cell Proliferation Regulatory ProcessFKBP12-rapamycin associated proteinFRAP1 protein, humanPhosphorylation

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MTOR wt Allele

Papers overview

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2017
2017
Biochemical analysis with measurements of bioactive ingredients of lemon varieties
The ‘Sweet Lemon’ and ‘Interdonato’ lemon varieties were evaluated based on their antioxidant activity, sugar, total phenol and… 
2016
2016
Antioxidant Activities Evaluation of Citrus Leaves Extracts from West Java-Indonesia Using DPPH and FRAP Assays
The aim of this research were to measure antioxidant activity from different polarities leaves extracts of five citrus using two… 
2015
2015
In vitro Antioxidant Capacities of Three Organs of Bitter gourd ( Momordica charantia L . ) Form West Java-Indonesia Using DPPH and FRAP Assays
The objectives of this research were to study antioxidant capacity from various organs extracts of bitter gourd using two methods… 
2012
2012
Targeting of mTORC 1 / 2 by the mTOR kinase inhibitor PP 242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment
Departments of 1Leukemia and 2Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center… 
2012
2012
Suppression of EphB4 improves the inhibitory effect of mTOR shRNA on the biological behaviors of ovarian cancer cells by down-regulating Akt phosphorylation
SummaryThe aim of the present study was to examine the effects of suppression of EphB4 and/or mTOR on the biological behaviors of… 
2012
2012
Suppression of EphB4 improves the inhibitory effect of mTOR shRNA on the biological behaviors of ovarian cancer cells by down-regulating Akt phosphorylation
The aim of the present study was to examine the effects of suppression of EphB4 and/or mTOR on the biological behaviors of… 
2011
2011
Targeted inhibition of mammalian target of rapamycin (mTOR) signaling pathway inhibits proliferation and induces apoptosis of laryngeal carcinoma cells in vitro.
AIM AND OBJECTIVE Laryngeal carcinoma is one of the most aggressive cancers of the head and neck region. The survival rate of… 
2005
2005
4 EBP 1 phosphorylation is mediated by the FRAP-p 70 s 6 k pathway and is independent of mitogen-activated protein kinase ( insulin / signal transduction / translational control )
It has previously been argued that the repressor of protein synthesis initiation factor 4E, 4E-BP1, is a direct in vivo target of… 
2000
2000
Ionizing radiation enhances double-strand-break repair in rapamycin-treated ataxia telangiectasia lymphoblasts
Purpose : Unlike normal cells, ataxia telangiectasia (A-T) cells do not exhibit enhanced double-strand-break (dsb)-repair… 
1998
1998
[Studies on deletion of 1p36 in oral squamous cell carcinoma].
  • T. Kimura
  • Nihon Jibiinkoka Gakkai kaiho
  • 1998
  • Corpus ID: 39125553
The deletion of region 36 in the short arm of chromosome 1 (1p36) was investigated in 18 patients with oral squamous cell… 
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