FAQ

MTOR wt Allele

Known as: Mechanistic Target of Rapamycin (Serine/Threonine Kinase) wt Allele, RAFT1, FLJ44809 
Human MTOR wild-type allele is located in the vicinity of 1p36.2 and is approximately 156 kb in length. This allele, which encodes serine/threonine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2012
012319742012

Related topics

Related topics

13 relations
1p36.2Adipocytokine Signaling PathwayCell Proliferation Regulatory ProcessERBB Family Signaling Pathway
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Broader (1)

MTOR gene

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
MTOR wt Allele
Signal Transduction
FRAP1 protein, human
Positive Regulation of Apoptosis
Cell Proliferation Regulatory Process
Phosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Standardized flavonoid-rich fraction of Artemisia princeps Pampanini cv. Sajabal induces apoptosis via mitochondrial pathway in human cervical cancer HeLa cells.
ETHNOPHARMACOLOGICAL RELEVANCE Artemisia princeps Pampanini is widely used in Eastern traditional medicine for the treatment of… (More)
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2010
2010
VEGF in the muscular layer of placental blood vessels: immuno-expression in preeclampsia and intrauterine growth restriction and its association with the antioxidant status.
The pathophysiology of preeclampsia (PE), a disorder occurring in 5% of all pregnancies, remains largely unknown, but early… (More)
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2006
2006
The evaluation of altered redox status in plasma and mitochondria of acute and chronic diabetic rats.
OBJECTIVES An increase in plasma oxidative stress and decreased mitochondrial lipid hydroperoxides may contribute to the… (More)
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2005
2005
Diminution of tissue lipid peroxidation in rats is related to the in vitro antioxidant capacity of wine.
Wine polyphenols could reinforce the endogenous antioxidant system, thereby diminishing oxidative damage. Studies in chronic… (More)
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2005
2005
Effects of Gingko biloba extract on gap junction changes induced by reperfusion/reoxygenation after ischemia/hypoxia in rat brain.
Gap junction communication between astrocytes plays an important role in the brain. The purpose of this study was to investigate… (More)
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Highly Cited
2002
Highly Cited
2002
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.
RAFT1/FRAP/mTOR is a key regulator of cell growth and division and the mammalian target of rapamycin, an immunosuppressive and… (More)
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Highly Cited
1994
Highly Cited
1994
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
The immunosuppressants rapamycin and FK506 bind to the same intracellular protein, the immunophilin FKBP12. The FKB12-FK506… (More)
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Highly Cited
1994
Highly Cited
1994
RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
Rapamycin is a potent immunosuppressant that blocks the G1/S transition in antigen-activated T cells and in yeast. The similar… (More)
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Review
1988
Review
1988
Acid phosphatase as a selective marker for a class of small sensory ganglion cells in several mammals: spinal cord distribution, histochemical properties, and relation to fluoride-resistant acid…
Fluoride-resistant acid phosphatase (FRAP) activity as characterized in rat and mouse was studied in sensory ganglion and spinal… (More)
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1974
1974
Fine structure and fluoride resistant acid phosphatase activity of electron dense sinusoid terminals in the substantia gelatinosa Rolandi of the rat after dorsal root transection
Fluoride resistant acid phosphatase (FRAP) activity of the rat substantia gelatinosa Rolandi is confined to electron dense… (More)
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