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The spindle-assembly checkpoint in space and time
- A. Musacchio, E. Salmon
- BiologyNature Reviews Molecular Cell Biology
- 1 May 2007
TLDR
GSK-3-selective inhibitors derived from Tyrian purple indirubins.
- L. Meijer, A. Skaltsounis, P. Greengard
- Biology, ChemistryChemistry & biology
- 1 December 2003
Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
- C. Ciferri, S. Pasqualato, A. Musacchio
- BiologyCell
- 2 May 2008
The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
- A. Musacchio
- BiologyCurrent Biology
- 19 October 2015
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex
- L. Hewitt, A. Tighe, Stephen S. Taylor
- BiologyThe Journal of cell biology
- 12 July 2010
To satisfy the mitotic checkpoint and drive chromosome congression, the Mps1 kinase lets go of kinetochores by phosphorylating itself in trans (see also related papers by Maciejowski et al. and…
Kinetochore Microtubule Dynamics and Attachment Stability Are Regulated by Hec1
- J. DeLuca, Walter E. Gall, C. Ciferri, D. Cimini, A. Musacchio, E. Salmon
- BiologyCell
- 1 December 2006
The Mad1/Mad2 Complex as a Template for Mad2 Activation in the Spindle Assembly Checkpoint
- A. Antoni, C. Pearson, A. Musacchio
- BiologyCurrent Biology
- 8 February 2005
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
- S. Santaguida, A. Tighe, A. M. D’Alise, Stephen S. Taylor, A. Musacchio
- BiologyThe Journal of cell biology
- 12 July 2010
Addition of reversine to dividing cells ejects Mad1 and the RZZ complex from unattached kinetochores and prevents resolution of incorrect chromosome–microtubule attachments (see also related papers…
Crystal structure of the tetrameric Mad1–Mad2 core complex: implications of a ‘safety belt’ binding mechanism for the spindle checkpoint
- Lucia Sironi, M. Mapelli, S. Knapp, A. Antoni, K. Jeang, A. Musacchio
- Chemistry, BiologyThe EMBO journal
- 15 May 2002
TLDR
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin.
- F. Sessa, M. Mapelli, A. Musacchio
- Biology, ChemistryMolecular cell
- 29 April 2005
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