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Somatomedins

Known as: Insulin-like growth factor, factor growth insulin-like, Somatomedin 
Bound to IGFBPs in the circulation, Insulin-Like Growth Factors (IGFs, Somatomedins) are a family of extracellular signaling peptides (potential… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (7)

Biomin HInsulin-Like Growth Factor IRecombinant Insulin-Like Growth Factorigf1 protein, zebrafish

Broader (4)

Blood ProteinsGrowth FactorGrowth SubstancesNeuropeptides
Cell Proliferation Regulatory ProcessExtracellular SpaceGrowth Factor GeneInsulin-Like Growth Factor Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2000
Review
2000
The contradictions of the insulin-like growth factor 1 receptor
In recent years, the type 1 insulin-like growth factor receptor (IGF-IR) has emerged as a receptor that plays a very important… 
Highly Cited
1997
Highly Cited
1997
Effects of a two-week physiological dehydroepiandrosterone substitution on cognitive performance and well-being in healthy elderly women and men.
The levels of dehydroepiandrosterone (DHEA) and its sulfate ester DHEAS decrease with age after a peak around 25 yr. Animal… 
Highly Cited
1997
Highly Cited
1997
Insulin-Like Growth Factor and Potassium Depolarization Maintain Neuronal Survival by Distinct Pathways: Possible Involvement of PI 3-Kinase in IGF-1 Signaling
Cultured cerebellar granule neurons die by apoptosis when switched from a medium containing an elevated level of potassium (K… 
Review
1994
Review
1994
Growth factors and growth modulators in human uterine endometrium: their potential relevance to reproductive medicine.
Highly Cited
1993
Highly Cited
1993
Growth Factors Prevent Mitochondrial Dysfunction, Loss of Calcium Homeostasis, and Cell Injury, but Not ATP Depletion in Hippocampal Neurons Deprived of Glucose
The mechanism of growth factor protection against metabolic/excitotoxic insults was examined. The time course of changes in ATP… 
Highly Cited
1993
Highly Cited
1993
Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product.
Wilms tumor is a pediatric neoplasm that arises from the metanephric blastema. The expression of the gene encoding insulin-like… 
Highly Cited
1989
Highly Cited
1989
High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum.
Highly Cited
1989
Highly Cited
1989
Nucleotide sequence and expression of a cDNA clone encoding a fetal rat binding protein for insulin-like growth factors.
Highly Cited
1987
Highly Cited
1987
Gonadotropins and estradiol stimulate immunoreactive insulin-like growth factor-I production by porcine granulosa cells in vitro.
Previous studies have established the ovarian granulosa cell as a site of insulin-like growth factor-I (IGF-I) secretion and… 
Highly Cited
1981
Highly Cited
1981
Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking.
The structure of receptors for insulin-like growth factors in rat liver plasma membranes and the BRL 3A2 rat liver cell line has… 
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