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Somatomedins

Known as: Insulin-like growth factor, factor growth insulin-like, Somatomedin 
Bound to IGFBPs in the circulation, Insulin-Like Growth Factors (IGFs, Somatomedins) are a family of extracellular signaling peptides (potential… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (7)

Biomin HInsulin-Like Growth Factor IRecombinant Insulin-Like Growth Factorigf1 protein, zebrafish

Broader (4)

Blood ProteinsGrowth FactorGrowth SubstancesNeuropeptides
Cell Proliferation Regulatory ProcessExtracellular SpaceGrowth Factor GeneInsulin-Like Growth Factor Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
Most traits and disorders have a multifactorial background indicating that they are controlled by environmental factors as well… 
Highly Cited
2002
Highly Cited
2002
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
Inactivation of tumour suppressor genes is central to the development of all common forms of human cancer. This inactivation… 
Review
2001
Review
2001
The somatomedin hypothesis: 2001.
Since the original somatomedin hypothesis was conceived, a number of important discoveries have allowed investigators to modify… 
Highly Cited
1999
Highly Cited
1999
Signals from the reproductive system regulate the lifespan of C. elegans
Understanding how the ageing process is regulated is a fascinating and fundamental problem in biology. Here we demonstrate that… 
Highly Cited
1994
Highly Cited
1994
Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
Aging in humans is accompanied by a progressive decline in the secretion of the adrenal androgens dehydroepiandrosterone (DHEA… 
Review
1994
Review
1994
Ovarian follicle atresia: a hormonally controlled apoptotic process.
GREATER THAN 99% of ovarian follicles undergo a degenerative process called atresia during reproductive life. Extending earlier… 
Highly Cited
1993
Highly Cited
1993
Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.
High levels of extracellular K+ ensure proper development and prolong survival of cerebellar granule neurons in culture. We find… 
Highly Cited
1991
Highly Cited
1991
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus
T-ASSOCIATED maternal effect (Tme) is the only known maternal-effect mutation in the mouse1,2. The defect is nuclear-encoded3 and… 
Highly Cited
1989
Highly Cited
1989
BENEFICIAL EFFECTS OF GROWTH HORMONE TREATMENT IN GH-DEFICIENT ADULTS
Highly Cited
1979
Highly Cited
1979
Dual control of cell growth by somatomedins and platelet-derived growth factor.
Quiescent BALB/c 3T3 cells exposed briefly to a platelet-derived growth factor (PDGF) become "competent" to replicate their DNA… 
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