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Somatomedins
Known as:
Insulin-like growth factor
, factor growth insulin-like
, Somatomedin
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Bound to IGFBPs in the circulation, Insulin-Like Growth Factors (IGFs, Somatomedins) are a family of extracellular signaling peptides (potential…
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National Institutes of Health
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Related topics
Related topics
31 relations
Narrower (7)
Biomin H
Insulin-Like Growth Factor I
Recombinant Insulin-Like Growth Factor
igf1 protein, zebrafish
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Broader (4)
Blood Proteins
Growth Factor
Growth Substances
Neuropeptides
Cell Proliferation Regulatory Process
Extracellular Space
Growth Factor Gene
Insulin-Like Growth Factor Receptor
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.
K. O'reilly
,
F. Rojo
,
+9 authors
N. Rosen
Cancer Research
2006
Corpus ID: 2903877
Stimulation of the insulin and insulin-like growth factor I (IGF-I) receptor activates the phosphoinositide-3-kinase/Akt/mTOR…
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Highly Cited
2003
Highly Cited
2003
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
C. Murphy
,
S. Mccarroll
,
+5 authors
C. Kenyon
Nature
2003
Corpus ID: 4424249
Ageing is a fundamental, unsolved mystery in biology. DAF-16, a FOXO-family transcription factor, influences the rate of ageing…
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Review
2001
Review
2001
The somatomedin hypothesis: 2001.
D. Le Roith
,
C. Bondy
,
S. Yakar
,
J. L. Liu
,
A. Butler
Endocrine reviews
2001
Corpus ID: 636598
Since the original somatomedin hypothesis was conceived, a number of important discoveries have allowed investigators to modify…
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Highly Cited
1997
Highly Cited
1997
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
D. Alessi
,
S. James
,
+4 authors
P. Cohen
Current Biology
1997
Corpus ID: 2094414
Highly Cited
1997
Highly Cited
1997
Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt
H. Dudek
,
S. R. Datta
,
+6 authors
M. Greenberg
Science
1997
Corpus ID: 7658844
A signaling pathway was delineated by which insulin-like growth factor 1 (IGF-1) promotes the survival of cerebellar neurons. IGF…
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Review
1995
Review
1995
Insulin-like growth factors and their binding proteins: biological actions.
J. I. Jones
,
D. Clemmons
Endocrine reviews
1995
Corpus ID: 10585320
I. Introduction THE insulin-like growth factors were discovered on the basis of their ability to stimulate cartilage sulfation…
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Highly Cited
1995
Highly Cited
1995
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
S. Kato
,
H. Endoh
,
+9 authors
P. Chambon
Science
1995
Corpus ID: 4662264
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER…
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Highly Cited
1993
Highly Cited
1993
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
Jeh-Ping Liu
,
J. Baker
,
Archlbald S. Perkins
,
E. Robertson
,
A. Efstratiadis
Cell
1993
Corpus ID: 42023430
Highly Cited
1993
Highly Cited
1993
Role of insulin-like growth factors in embryonic and postnatal growth
J. Baker
,
Jeh-Ping Liu
,
E. Robertson
,
A. Efstratiadis
Cell
1993
Corpus ID: 20758798
Highly Cited
1993
Highly Cited
1993
Role for DNA methylation in genomic imprinting
E. Li
,
C. Beard
,
R. Jaenisch
Nature
1993
Corpus ID: 4311091
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