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Somatomedins

Known as: Insulin-like growth factor, factor growth insulin-like, Somatomedin 
Bound to IGFBPs in the circulation, Insulin-Like Growth Factors (IGFs, Somatomedins) are a family of extracellular signaling peptides (potential… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (7)

Biomin HInsulin-Like Growth Factor IRecombinant Insulin-Like Growth Factorigf1 protein, zebrafish

Broader (4)

Blood ProteinsGrowth FactorGrowth SubstancesNeuropeptides
Cell Proliferation Regulatory ProcessExtracellular SpaceGrowth Factor GeneInsulin-Like Growth Factor Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Explorer Pleiotropic effects of extended blockade of CSF 1 R signaling in adult mice
We investigated the role of CSF1R signaling in adult mice using prolonged treatment with anti-CSF1R antibody. Mutation of the… 
Highly Cited
1995
Highly Cited
1995
Effects of recombinant porcine somatotropin on placental size, fetal growth, and IGF-I and IGF-II concentrations in pigs.
The objective of this study was to determine the effects of recombinant porcine somatotropin (rpST) on placental size, fetal… 
1994
1994
Catecholamines stimulate the synthesis and release of insulin-like growth factor binding protein-1 (IGFBP-1) by fetal sheep liver in vivo.
In fetal sheep, prolonged hypoxia (for 24 h) induced by a reduction in maternal uterine artery blood flow, increases insulin-like… 
Highly Cited
1991
Highly Cited
1991
Insulin-like growth factor binding proteins: roles in regulating IGF physiology.
Insulin-like growth factor binding proteins (IGFBPs) are soluble proteins present in in extracellular fluids. They have high… 
Highly Cited
1991
Highly Cited
1991
Insulin-like growth factor-I receptors in human hyperplastic prostate tissue: characterization, tissue localization, and their modulation by chronic treatment with a gonadotropin-releasing hormone…
Insulin-like growth factor I (IGF-I) receptors were characterized in membranes obtained from prostate tissue of patients affected… 
Highly Cited
1989
Highly Cited
1989
Insulin-Receptor and Apolipoprotein Genes Contribute to Development of NIDDM in Chinese Americans
The frequencies of restriction-fragment-length polymorphism (RFLP) alleles as well as RFLP haplotypes at six genetic loci… 
Highly Cited
1987
Highly Cited
1987
Stimulation of intestinal epithelial cell proliferation in culture by growth factors in human and ruminant mammary secretions.
Samples of human and ruminant mammary secretions stimulated the proliferation of rat intestinal epithelial (RIE-1) cells in… 
Highly Cited
1986
Highly Cited
1986
Rapid microassay for protein kinase C translocation in Swiss 3T3 cells.
The Ca2+/phosphatidylserine-stimulated protein kinase C (PKC) appears to exist as interconvertible inactive, soluble and active… 
Highly Cited
1985
Highly Cited
1985
Human growth hormone gene deletion without antibody formation or growth arrest during treatment--a new disease entity?
Using restriction endonuclease analysis of genomic DNA hybridized to a human chorionic somatomammotropin (hCS) complementary (c… 
Highly Cited
1985
Highly Cited
1985
Antibody against acid-stable insulin-like growth factor binding protein detects 150,000 mol wt growth hormone-dependent complex in human plasma.
In order to measure the 150,000 mol wt binding complex for insulin-like growth factors in human plasma without the need for… 
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