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Growth Factor

Known as: Growth factors, Growth Factors, Proteins, Mitogen 
Substances made by the body that function to regulate cell division and cell survival. Some growth factors are also produced in the laboratory and… 
National Institutes of Health

Related topics

Related topics

48 relations
ActivinsBecaplerminColony-Stimulating FactorsEPO protein, human

Narrower (10)

Angiogenesis FactorAngiopoietinsEpidermal Growth FactorFibroblast Growth Factor 7

Papers overview

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Highly Cited
2010
Highly Cited
2010
Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent
We previously reported a vascular endothelial growth factor (VEGF) autocrine loop in head and neck squamous cell carcinoma (HNSCC… 
Highly Cited
2001
Highly Cited
2001
Relation of vascular endothelial growth factor production to expression and regulation of hypoxia-inducible factor-1 alpha and hypoxia-inducible factor-2 alpha in human bladder tumors and cell lines.
Hypoxia is an important regulator of vascular endothelial growth factor (VEGF) expression, and VEGF is associated with poor… 
Review
2001
Review
2001
The evolution of fluoropyrimidine therapy: from intravenous to oral.
Chemotherapy for advanced colorectal cancer is based on i.v. 5-fluorouracil (5-FU). Numerous attempts have been made to increase… 
Highly Cited
2000
Highly Cited
2000
Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line.
The expression of vascular endothelial growth factor (VEGF), a highly potent angiogenic molecule, is thought to be correlated… 
Highly Cited
1998
Highly Cited
1998
Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin‐binding EGF‐like growth factor independently of protein kinase C
The phorbol ester, tetradecanoyl‐phorbol 13‐acetate (TPA), stimulates rapid proteolytic processing of the transmembrane, pro… 
Highly Cited
1996
Highly Cited
1996
Role of endothelin as a mitogen in experimental glomerulonephritis in rats.
Recent studies have revealed that endothelin-1 (ET-1) is a potent mitogen for mesangial cells in vitro. To determine whether ET-1… 
Highly Cited
1989
Highly Cited
1989
All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.
Human epidermal keratinocytes were established in culture using a low-Ca2+ (0.15 mM), serum-free keratinocyte growth medium (KGM… 
Highly Cited
1987
Highly Cited
1987
Construction of a novel oncogene based on synthetic sequences encoding epidermal growth factor.
The autocrine model postulates that constitutive release of a mitogenic growth factor can lead to uncontrolled proliferation and… 
Highly Cited
1986
Highly Cited
1986
Purification and partial sequence analysis of insulin-like growth factor-1 from bovine colostrum.
Growth-promoting activity in bovine colostrum has been detected as the capacity to stimulate protein synthesis in L6 myoblasts… 
Highly Cited
1979
Highly Cited
1979
Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation
THERE is much evidence that interaction with specific cell surface receptors is a key event in the action of polypeptide hormones… 
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