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EPO protein, human
Known as:
erythropoietin protein, human
, Erythropoietin
, Epoetin
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A substance that is naturally produced by the kidneys, and that stimulates the bone marrow to make red blood cells. When erythropoietin is made in…
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National Institutes of Health
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Related topics
Related topics
25 relations
Bone Marrow
Cell Differentiation process
Cytokine Gene
Cytokine Receptor Binding
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Broader (1)
Erythropoietin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer
J. Rizzo
,
M. Brouwers
,
+10 authors
M. Somerfield
2010
Corpus ID: 1749275
1Medical College of Wisconsin, Milwaukee, WI; 2McMaster University, Hamilton, Ontario, Canada; 3American Society of Clinical…
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Review
2009
Review
2009
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.
T. Hercus
,
Daniel Thomas
,
+4 authors
Angel F. Lopez
Blood
2009
Corpus ID: 11516727
Already 20 years have passed since the cloning of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha…
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Highly Cited
2007
Highly Cited
2007
Efficacy and safety of epoetin alfa in critically ill patients.
H. Corwin
,
A. Gettinger
,
+8 authors
M. Corwin
New England Journal of Medicine
2007
Corpus ID: 8589837
BACKGROUND Anemia, which is common in the critically ill, is often treated with red-cell transfusions, which are associated with…
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Highly Cited
2007
Highly Cited
2007
Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy.
D. Henry
,
N. Dahl
,
M. Auerbach
,
S. Tchekmedyian
,
L. Laufman
The Oncologist
2007
Corpus ID: 767864
PURPOSE To evaluate the safety and efficacy of intravenous (IV) sodium ferric gluconate complex (FG), oral ferrous sulfate, or no…
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Review
2003
Review
2003
Epoetin alfa treatment results in clinically significant improvements in quality of life in anemic cancer patients when referenced to the general population.
D. Cella
,
M. Zagari
,
C. Vandoros
,
D. Gagnon
,
H. Hurtz
,
J. Nortier
Journal of Clinical Oncology
2003
Corpus ID: 31634237
PURPOSE Anemia, highly common among cancer patients, is often an underlying cause of cancer-related fatigue and other quality-of…
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Highly Cited
2002
Highly Cited
2002
Randomized, controlled trial of darbepoetin alfa for the treatment of anemia in hemodialysis patients.
A. Nissenson
,
S. Swan
,
+6 authors
B. Maroni
American Journal of Kidney Diseases
2002
Corpus ID: 22915668
BACKGROUND Darbepoetin alfa (Aranesp; Amgen, Thousand Oaks, CA) is a new erythropoiesis-stimulating protein with a threefold…
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Review
2001
Review
2001
Epoetin treatment of anemia associated with cancer therapy: a systematic review and meta-analysis of controlled clinical trials.
J. Seidenfeld
,
Margaret Piper
,
+8 authors
Naomi Aronson
Journal of the National Cancer Institute
2001
Corpus ID: 37181777
Epoetin treatment offers an attractive but costly alternative to red blood cell transfusion for managing anemia associated with…
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Highly Cited
2001
Highly Cited
2001
Efficacy of epoetin alfa in the treatment of anaemia of multiple myeloma
F. Dammacco
,
G. Castoldi
,
S. Rödjer
British Journal of Haematology
2001
Corpus ID: 41084194
Effects of epoetin alfa on transfusions, haemoglobin (Hb) and quality of life (QOL) were evaluated in a placebo‐controlled study…
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Highly Cited
1996
Highly Cited
1996
The intensity of hemodialysis and the response to erythropoietin in patients with end-stage renal disease.
O. Ifudu
,
Joseph Feldman
,
Eli A. Friedman
New England Journal of Medicine
1996
Corpus ID: 21211739
BACKGROUND Anemia (characterized by a hematocrit of 30 percent or lower) persists in 40 to 60 percent of patients treated for end…
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Highly Cited
1987
Highly Cited
1987
Synergy of interleukin 1 and granulocyte colony-stimulating factor: in vivo stimulation of stem-cell recovery and hematopoietic regeneration following 5-fluorouracil treatment of mice.
M. Moore
,
D. Warren
Proceedings of the National Academy of Sciences…
1987
Corpus ID: 6253971
The human bladder carcinoma cell line 5637 produces hematopoietic growth factors [granulocyte and granulocyte/macrophage colony…
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