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Becaplermin

Known as: platelet-derived growth factor BB, SH-POLYPEPTIDE-59, rhPDGF-BB 
The recombinant analog of endogenous beta (B) chain of the cytokine platelet-derived growth factor (PDGF). Synthesized primarily by megakaryocytes… 
National Institutes of Health

Related topics

Related topics

17 relations

Broader (2)

Angiogenesis Inducing AgentsProto-Oncogene Proteins c-sis
Becaplermin 0.0001 MG/MG Topical Gel [Regranex]Cell ProliferationCommunicable DiseasesDrug Allergy

Narrower (1)

Regranex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Estimation of the use of fibrin and collagen membranes as carriers for platelet-derived growth factor-BB (PDGF-BB) in the presence of amoxicillin.
The effect of homogeneous fibrin (Fb), collagen (Coll) and composite fibrin-heparin (Fb-Hp), fibrin-collagen (Fb-Coll) membranes… 
2013
2013
Postextraction ridge preservation and augmentation with mineralized allograft with or without recombinant human platelet-derived growth factor BB (rhPDGF-BB): a consecutive case series.
In an attempt to reduce postextraction alveolar bone resorption, ridge preservation and augmentation procedures have become… 
2009
2009
Vertical ridge augmentation with the use of recombinant human platelet-derived growth factor-BB and bovine bone mineral: a case report.
The present paper reports on a patient who underwent vertical ridge augmentation using recombinant human platelet-derived growth… 
2008
2008
[Expression and clinical implication of platelet-derived growth factor-D and platelet-derived growth factor-beta in childhood IgA nephropathy].
OBJECTIVE To investigate the clinical implication of platelet-derived growth factor (PDGF)-D and PDGF-beta in IgA nephropathy in… 
2006
2006
Control of the Expression of csis mRNA in Human Glioblastoma Cells by Phorbol Ester and Transforming Growth Factor ß 1
The regulation of c-vi.v oncogene expression in human glioblastoma cell line Al 72 has been investigated using a sensitive RNA… 
1987
1987
Effects of interferon-gamma on proto-oncogene expression during induction of human monocytic differentiation.
Activation of the proto-oncogenes c-fos, c-fms, and c-sis has been associated with monocytic differentiation. In the present… 
1987
1987
Genetic organization of the c-sis transcription unit.
The structure and genetic organization of the transcription unit of the c-sis proto-oncogene was determined. Comparative… 
Highly Cited
1986
Highly Cited
1986
Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation.
Phorbol esters induce the differentiation of human myeloid leukemia cells HL-60 and U-937 along the monocytic-macrophage lineage… 
1986
1986
Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea
Long-term culturing of brain cells from neonatal BD-IX rats after transplacental treatment with N-ethyl-N-nitrosourea (ENU… 
1984
1984
Localization of the human c-sis oncogene in Ph1-positive and Ph1-negative chronic myelocytic leukemia by in situ hybridization.
Oncogenes are a group of evolutionary conserved cellular genes (c-onc) homologous to the transforming genes of oncogenic…