Becaplermin

Known as: platelet-derived growth factor BB, SH-POLYPEPTIDE-59, rhPDGF-BB 
The recombinant analog of endogenous beta (B) chain of the cytokine platelet-derived growth factor (PDGF). Synthesized primarily by megakaryocytes… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cancer patients treated with antiangiogenic multitargeted receptor tyrosine kinase (RTK) inhibitors show increased levels of… (More)
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Highly Cited
2005
Highly Cited
2005
Pulmonary fibrosis is the consequence of a variety of diseases with no satisfying treatment option. Therapy-induced fibrosis also… (More)
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Highly Cited
2004
Highly Cited
2004
The human endometrium regenerates from the lower basalis layer, a germinal compartment that persists after menstruation to give… (More)
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Highly Cited
2003
Highly Cited
2003
Tumor-infiltrating blood vessels deviate morphologically and biochemically from normal vessels, raising the prospect of selective… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Vascular smooth muscle cell proliferation plays an important role in the development of atherosclerosis. We previously… (More)
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Highly Cited
1999
Highly Cited
1999
The results of a combined analysis and separate analyses of four multicenter, randomized, parallel group studies that evaluated… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To compare the efficacy and safety of topically applied recombinant human platelet-derived growth factor-BB (rhPDGF-BB… (More)
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Highly Cited
1997
Highly Cited
1997
PDGF-A(-/-) mice lack lung alveolar smooth muscle cells (SMC), exhibit reduced deposition of elastin fibres in the lung… (More)
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Highly Cited
1996
Highly Cited
1996
A mouse platelet-derived growth factor A chain (PDGF-A) null allele is shown to be homozygous lethal, with two distinct… (More)
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Highly Cited
1992
Highly Cited
1992
Platelet-derived growth factor (PDGF) is a mitogen and chemoattractant for vascular smooth muscle cells (SMC) in vitro, but its… (More)
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