Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation
- R. Chemelli, J. Willie, M. Yanagisawa
- Biology, PsychologyCell
- 1 August 1999
Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.
- Y. Kisanuki, R. Hammer, J. Miyazaki, S. Williams, J. Richardson, M. Yanagisawa
- BiologyDevelopmental Biology
- 15 February 2001
Tie2-Cre transgenic mice are a new genetic tool for the analyses of endothelial cell-lineage and endothelialcell-specific gene targeting and lacZ staining in Tie2- Cre;CAG-CAT-Z embryos is consistent with endocardial-mesenchymal transformation in the atrioventricular canal and outflow tract regions.
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21.
- T. Inagaki, Paul A. Dutchak, S. Kliewer
- Biology, MedicineCell Metabolism
- 6 June 2007
Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2
- M. Trommsdorff, M. Gotthardt, J. Herz
- BiologyCell
- 11 June 1999
Synaptic assembly of the brain in the absence of neurotransmitter secretion.
- M. Verhage, A. Maia, T. Südhof
- BiologyScience
- 4 February 2000
Synaptic connectivity does not depend on neurotransmitter secretion, but its maintenance does, and neurotransmitter secretion probably functions to validate already established synaptic connections.
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
- M. Geppert, Y. Goda, T. Südhof
- BiologyCell
- 18 November 1994
Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα
- D. Peet, S. Turley, D. Mangelsdorf
- BiologyCell
- 29 May 1998
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
- B. Samuel, A. Shaito, J. Gordon
- BiologyProceedings of the National Academy of Sciences
- 28 October 2008
Functional genomic, biochemical, and physiologic studies reveal that Gpr41 is a regulator of host energy balance through effects that are dependent upon the gut microbiota.
Essential functions of synapsins I and II in synaptic vesicle regulation
- T. Rosahl, D. Spillane, T. Südhof
- BiologyNature
- 8 June 1995
Synthetic synapsins are not required for neurite outgrowth, synaptogenesis or the basic mechanics of synaptic vesicle traffic, but are essential for accelerating this traffic during repetitive stimulation.
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.
- S. Ishibashi, M. Brown, J. Goldstein, R. Gerard, R. Hammer, J. Herz
- Biology, MedicineJournal of Clinical Investigation
- 1 August 1993
It is concluded that the LDL receptor is responsible in part for the low levels of VLDL, IDL, and LDL in wild-type mice and that adenovirus-encoded LDL receptors can acutely reverse the hypercholesterolemic effects of LDL receptor deficiency.
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