Insulin-Like Growth Factor Receptor

Known as: Receptors, Somatomedin [Chemical/Ingredient], Receptors, Insulin-Like Growth Factors, Insulin Like Growth Factor Receptor 
Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Insulin receptor signalling has a central role in mammalian biology, regulating cellular metabolism, growth, division… (More)
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Highly Cited
2012
Highly Cited
2012
Over the past decade, encouraging preclinical and early clinical data concerning the relevance of the insulin receptor/insulin… (More)
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Highly Cited
2008
Highly Cited
2008
Increasing the mechanical load on skeletal muscle results in increased expression of insulin-like growth factor I (IGF-I), which… (More)
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Highly Cited
2007
Highly Cited
2007
The insulin receptor substrate-1 (IRS-1), a docking protein for both the type 1 insulin-like growth factor receptor (IGF-IR) and… (More)
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Highly Cited
2005
Highly Cited
2005
Both the epidermal growth factor receptor (EGFR) and the insulin-like growth factor receptor (IGFR) have been implicated in the… (More)
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Review
2000
Review
2000
The type 1 insulin-like growth factor receptor (IGF-1R), a transmembrane tyrosine kinase, is widely expressed across many cell… (More)
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Highly Cited
1999
Highly Cited
1999
The type 1 insulin-like growth factor receptor (IGF-1R), activated by its ligands, protects several cell types from a variety of… (More)
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Highly Cited
1992
Highly Cited
1992
Insulin-like growth factors have a number of potent trophic effects on cultured neural tissue and most if not all of these… (More)
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Highly Cited
1991
Highly Cited
1991
Insulin-like growth factors (IGFs) are potent mitogens that bind with high affinity and specificity to IGF receptors and IGF… (More)
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Review
1989
Review
1989
Insulin and the insulin-like growth factors (I and II) are homologous peptides essential to normal metabolism as well as growth… (More)
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