IGF1R protein, human

Known as: IGF-1R, IGF1R, Insulin-Like Growth Factor 1 Receptor 
Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
The H19 large intergenic non-coding RNA (lincRNA) is one of the most highly abundant and conserved transcripts in mammalian… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE The type 1 insulin-like growth factor 1 receptor (IGF-1R) has been implicated in the pathogenesis of the Ewing sarcoma… (More)
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Highly Cited
2011
Highly Cited
2011
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer of immature T cells that often shows aberrant activation of… (More)
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Highly Cited
2010
Highly Cited
2010
miR-7 (microRNA-7) has been characterized as a tumour suppressor in several human cancers. It targets a number of proto-oncogenes… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND SCH 717454 (19D12) is a fully human antibody directed against the insulin-like growth factor 1 receptor (IGF-1R… (More)
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Highly Cited
2006
Highly Cited
2006
Sir2 is an NAD+-dependent deacetylase that regulates lifespan in yeast, worms and flies. The mammalian orthologs of Sir2 include… (More)
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Highly Cited
2003
Highly Cited
2003
Studies in invertebrates have led to the identification of a number of genes that regulate lifespan, some of which encode… (More)
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Highly Cited
1996
Highly Cited
1996
The cation-dependent and cation-independent mannose 6-phosphate receptors (CD- and CI-MPRs) bind the phosphomannosyl recognition… (More)
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Highly Cited
1994
Highly Cited
1994
The growth of human melanoma cells FO-1 in nude mice is strongly inhibited or even abrogated when the cells are stably… (More)
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Highly Cited
1993
Highly Cited
1993
Newborn mice homozygous for a targeted disruption of insulin-like growth factor gene (Igf-1) exhibit a growth deficiency similar… (More)
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