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IGF1R protein, human

Known as: IGF-1R, IGF1R, Insulin-Like Growth Factor 1 Receptor 
Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and… 
National Institutes of Health

Related topics

Related topics

30 relations
Biological MarkersCell Cycle ControlCell Differentiation processCell Proliferation

Broader (2)

Insulin-Like Growth Factor ReceptorInsulin-Like-Growth Factor I Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MicroRNA ‐ 320 a is downregulated in non ‐ small cell lung cancer and suppresses tumor cell growth and invasion by directly targeting insulin ‐ like growth factor 1 receptor
Accumulating evidence has demonstrated that microRNAs (miRs/miRNAs) are implicated in carcinogenesis and cancer progression, and… 
2016
2016
miR-448 suppresses proliferation and invasion by regulating IGF1R in colorectal cancer cells.
Accumulating evidence has demonstrated that miR-448 expression was downregulated, and exerted tumor suppressor roles in several… 
2014
2014
Familial short stature is associated with a novel dominant‐negative heterozygous insulin‐like growth factor 1 receptor (IGF1R) mutation
Type-1 insulin-like growth factor receptor (IGF1R) plays a critical role in foetal and postnatal growth. Several heterozygous… 
2014
2014
Caffeine and caffeic acid inhibit growth and modify estrogen receptor ( ER ) and insulin-like growth factor I receptor ( IGF-IR ) levels in human breast cancer
1 Lund University and Skåne University Hospital, Department of Clinical Sciences, Lund, Division of Oncology and Pathology, Lund… 
2012
2012
Binding Inhibition Between Igf1r and Igf1 by Catechin of Black Tea
The natural compound of black tea is used as an alternative of obesity therapies in the world; particularly, the catechin family… 
Review
2012
Review
2012
Molecular imaging of insulin-like growth factor 1 receptor in cancer.
Insulin-like growth factor 1 receptor (IGF1R) plays an important role in proliferation, apoptosis, angiogenesis, and tumor… 
2011
2011
Molecular Medicine in Practice Evasion Mechanisms to Igf 1 r Inhibition in Rhabdomyosarcoma
Inhibition of the insulin-like growth factor 1 receptor (Igf1r) is an approach being taken in clinical trials to overcome the… 
2010
2010
ENHANCED EFFICACY OF IGF1R INHIBITION IN PAEDIATRIC GLIOBLASTOMA BY COMBINATORIAL TARGETING OF PDGFRALPHA/BETA
2010
2010
Therapy: An unhelpful hand
ei l Sm it h Increased signalling through the insulin-like growth factor (IGF) pathway has been implicated in the progression of… 
Review
2007
Review
2007
New targets for cancer therapy: minireview reprints collection
The minireviews programme was launched in British Journal of Cancer in 2002 and has gradually gathered pace: we have now… 
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