Skip to search formSkip to main contentSkip to account menu

IGF1R protein, human

Known as: IGF-1R, IGF1R, Insulin-Like Growth Factor 1 Receptor 
Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and… 
National Institutes of Health

Related topics

Related topics

30 relations
Biological MarkersCell Cycle ControlCell Differentiation processCell Proliferation

Broader (2)

Insulin-Like Growth Factor ReceptorInsulin-Like-Growth Factor I Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells.
Highly Cited
2008
Highly Cited
2008
CD117 (c-kit) is aberrantly expressed in a subset of MGUS and multiple myeloma with unexpectedly good prognosis.
Highly Cited
2008
Highly Cited
2008
A Comparative Structural Bioinformatics Analysis of the Insulin Receptor Family Ectodomain Based on Phylogenetic Information
The insulin receptor (IR), the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor-related receptor (IRR) are… 
Highly Cited
2007
Highly Cited
2007
Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.
Highly Cited
2005
Highly Cited
2005
CD221 (IGF-1R) is aberrantly expressed in multiple myeloma, in relation to disease severity.
We investigated the expression of insulin-like growth factor-1 receptor (CD221) in normal, reactive and malignant plasma cells… 
Review
2000
Review
2000
A new concept in neurodegeneration: TNFalpha is a silencer of survival signals.
The p55 receptor for the pro-inflammatory cytokine tumor necrosis factor alpha (TNFalpha) is best characterized by its ability to… 
Highly Cited
1996
Highly Cited
1996
Transformation by human papillomavirus 16 E6 and E7: role of the insulin-like growth factor 1 receptor.
Human papillomavirus-16 E6 and E7 inactivate the tumor suppressors p53 and pRB, respectively, and cooperate during malignant… 
Highly Cited
1996
Highly Cited
1996
Inhibition of rat C6 glioblastoma tumor growth by expression of insulin-like growth factor I receptor antisense mRNA
Abstract The expression of insulin-like growth factor I receptor (IGF-IR) antisense mRNA inhibits the growth of C6 rat… 
Highly Cited
1993
Highly Cited
1993
Ring chromosome 15 involving deletion of the insulin-like growth factor 1 receptor gene in a patient with features of Silver-Russell syndrome.
An 11-year-old girl with de novo r(15) (p12q26.3) with a clinical diagnosis of Silver-Russell syndrome (SRS) is presented. She… 
Highly Cited
1991
Highly Cited
1991
The protooncogene c-myb increases the expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor messenger RNAs by a transcriptional mechanism.
The protooncogene c-myb is the cellular equivalent of the viral transforming oncogene v-myb. When human c-myb is constitutively… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)