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IGF1R protein, human

Known as: IGF-1R, IGF1R, Insulin-Like Growth Factor 1 Receptor 
Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The H19 large intergenic non-coding RNA (lincRNA) is one of the most highly abundant and conserved transcripts in mammalian… Expand
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Highly Cited
2011
Highly Cited
2011
Cortical development depends on the active integration of cell-autonomous and extrinsic cues, but the coordination of these… Expand
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Highly Cited
2003
Highly Cited
2003
Studies in invertebrates have led to the identification of a number of genes that regulate lifespan, some of which encode… Expand
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Highly Cited
2002
Highly Cited
2002
To examine the local actions of IGF signaling in skeletal tissue in a physiological context, we have used Cre-mediated… Expand
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Review
2001
Review
2001
Targeted gene mutations have established distinct, yet overlapping, developmental roles for receptors of the insulin/IGF family… Expand
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Highly Cited
1999
Highly Cited
1999
Insulin receptor substrates (Irs proteins) mediate the pleiotropic effects of insulin and Igf-1 (insulin-like growth factor-1… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT The type 1 insulin-like growth factor receptor (IGF-1R), activated by its ligands, protects several cell types from a… Expand
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Highly Cited
1996
Highly Cited
1996
The cation-dependent and cation-independent mannose 6-phosphate receptors (CD- and CI-MPRs) bind the phosphomannosyl recognition… Expand
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Highly Cited
1993
Highly Cited
1993
Newborn mice homozygous for a targeted disruption of insulin-like growth factor gene (Igf-1) exhibit a growth deficiency similar… Expand
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Highly Cited
1993
Highly Cited
1993
Fibroblast cell lines were established from mouse embryos homozygous for a targeted disruption of the Igf1r gene, encoding the… Expand
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