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IGF1R gene

Known as: JTK13, MGC18216, IGF1R 
This gene is involved in the regulation of apoptosis and cell proliferation and plays a role in cellular transformation and malignancy.
National Institutes of Health

Related topics

Related topics

12 relations
Cell Cycle ControlCell Proliferation Regulatory ProcessCell SurvivalHomo sapiens

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Insulin-Like Growth Factor Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells
Melanoma is notoriously resistant to all current modalities of cancer therapies including chemotherapy. In recent years… 
2017
2017
[Co-culture with umbilical cord mesenchymal stem cells promotes the synthesis and mechnism of milk protein in bovine mammary epithelial cells].
Objective To explore the possible mechanism of umbilical cord mesenchymal stem cells (UCMSCs) regulating milk protein synthesis… 
2017
2017
Global transcriptomic analysis of induced cardiomyocytes predicts novel regulators for direct cardiac reprogramming
Heart diseases are the most significant cause of morbidity and mortality in the world. De novo generated cardiomyocytes (CMs) are… 
2015
2015
Wogonin increases doxorubicin sensitivity by down-regulation of IGF-1R/AKT signaling pathway in human breast cancer.
Currently drug resistance has remained a major challenge in successful breast cancer therapy. Wogonin, one of the active… 
2014
2014
Novel Secondary Somatic Mutations in Ewing's Sarcoma and Desmoplastic Small Round Cell Tumors
Background Ewing's sarcoma (ES) and desmoplastic small round cell tumors (DSRCT) are small round blue cell tumors driven by an N… 
Review
2013
Review
2013
Esophageal carcinoma: are modern targeted therapies shaking the rock?
Purpose of review Our current review aims to outline recent progress in the development of modern targeted therapeutic regimens… 
2012
2012
Short-time glucose exposure of embryonic carcinoma cells impairs their function as terminally differentiated cardiomyocytes.
2010
2010
IGF-1 and IGF-1R gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds
The aim of this study was to determine the allele and genotype frequencies of the Insulin like growth factor 1 gene (IGF-1) and… 
2005
2005
Inhibition of the insulin like growth factor 1 receptor by a specific monoclonal antibody in multiple myeloma
3048 Background: The Insulin Like Growth Factor 1 Receptor (IGF-1R) plays a key role in multiple myeloma (MM). IGF-1 is a growth… 
2001
2001
Effect of IGFBP-3 on IGF- and IGF-analogue-induced insulin-like growth factor-I receptor (IGFIR) signalling.
Insulin-like growth factor binding protein-3 (IGFBP-3) binds IGF-I and IGF-II with high affinity, at least an order of magnitude… 
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