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IGF1R gene

Known as: JTK13, MGC18216, IGF1R 
This gene is involved in the regulation of apoptosis and cell proliferation and plays a role in cellular transformation and malignancy.
National Institutes of Health

Related topics

Related topics

12 relations
Cell Cycle ControlCell Proliferation Regulatory ProcessCell SurvivalHomo sapiens

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Insulin-Like Growth Factor Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells
Melanoma is notoriously resistant to all current modalities of cancer therapies including chemotherapy. In recent years… 
2018
2018
Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)
Abstract Introduction: Growth failure is a common consequence in small for gestational age (SGA) children. Patients and Methods… 
2018
2018
Proteomic profiling of phosphatidylinositol 3-kinase (PI3K) altered metastatic colorectal cancer (mCRC) after protein kinase B (Akt) inhibition: Insulin like growth factor 1 receptor (IGF1R) mediates…
3549Background: We have reported earlier that Akt inhibition is clinically ineffective as monotherapy in PI3K altered (PIK3CA… 
2017
2017
[Co-culture with umbilical cord mesenchymal stem cells promotes the synthesis and mechnism of milk protein in bovine mammary epithelial cells].
Objective To explore the possible mechanism of umbilical cord mesenchymal stem cels( UCMSCs) regulating milk protein synthesis in… 
2014
2014
Abstract 2863: TMPRSS2-ERG influences IGF-1R expression and affects its prognostic value in prostate cancer
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA INTRODUCTION: Insulin like growth factor 1 receptor (IGF… 
Review
2013
Review
2013
Esophageal carcinoma: are modern targeted therapies shaking the rock?
Purpose of review Our current review aims to outline recent progress in the development of modern targeted therapeutic regimens… 
2012
2012
Short-time glucose exposure of embryonic carcinoma cells impairs their function as terminally differentiated cardiomyocytes.
2012
2012
Abstract 708: Clinical significance of insulin-like growth factor 1 receptor (IGF1R) expression in pancreatic cancer
Introduction: Insulin like growth factor 1 receptor (IGF1R) reported to be overexpressed in some types of human carcinomas… 
2010
2010
IGF-1 and IGF-1R gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds
The aim of this study was to determine the allele and genotype frequencies of the Insulin like growth factor 1 gene (IGF-1) and… 
2005
2005
Inhibition of the insulin like growth factor 1 receptor by a specific monoclonal antibody in multiple myeloma
3048 Background: The Insulin Like Growth Factor 1 Receptor (IGF-1R) plays a key role in multiple myeloma (MM). IGF-1 is a growth… 
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