Global transcriptomic analysis of induced cardiomyocytes predicts novel regulators for direct cardiac reprogramming

@article{Talkhabi2017GlobalTA,
  title={Global transcriptomic analysis of induced cardiomyocytes predicts novel regulators for direct cardiac reprogramming},
  author={Mahmood Talkhabi and Seyed Morteza Razavi and Ali Akbar Salari},
  journal={Journal of Cell Communication and Signaling},
  year={2017},
  volume={11},
  pages={193-204}
}
Heart diseases are the most significant cause of morbidity and mortality in the world. De novo generated cardiomyocytes (CMs) are a great cellular source for cell-based therapy and other potential applications. Direct cardiac reprogramming is the newest method to produce CMs, known as induced cardiomyocytes (iCMs). During a direct cardiac reprogramming, also known as transdifferentiation, non-cardiac differentiated adult cells are reprogrammed to cardiac identity by forced expression of cardiac… CONTINUE READING
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