Scaffold protein

Known as: Scaffolding Protein 
Scaffolding Proteins participate in many cellular functions by serving as a supportive base that spatially or temporally organizes, juxtaposes… (More)
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Signal specificity of multifunctional enzymes is achieved through protein-protein interactions involving specific domains on… (More)
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Highly Cited
2007
Highly Cited
2007
SHANK3 (also known as ProSAP2) regulates the structural organization of dendritic spines and is a binding partner of neuroligins… (More)
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Review
2002
Review
2002
Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences… (More)
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Highly Cited
2001
Highly Cited
2001
The c-Jun N-terminal kinase (JNK) signal transduction pathway is activated in response to the exposure of cells to environmental… (More)
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Highly Cited
2001
Highly Cited
2001
We have identified a novel, highly conserved protein of 14 kD copurifying with late endosomes/lysosomes on density gradients. The… (More)
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Highly Cited
2000
Highly Cited
2000
In addition to preventing crosstalk among related signaling pathways, scaffold proteins might facilitate signal transduction by… (More)
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Highly Cited
1999
Highly Cited
1999
NMDA receptors are linked to intracellular cytoskeletal and signaling molecules via the PSD-95 protein complex. We report a novel… (More)
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Highly Cited
1998
Highly Cited
1998
The c-Jun NH2-terminal kinase (JNK) group of mitogen-activated protein (MAP) kinases is activated by the exposure of cells to… (More)
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Highly Cited
1997
Highly Cited
1997
Caveolin, a 21-24-kDa integral membrane protein, is a principal component of caveolae membranes. We have suggested that caveolin… (More)
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Highly Cited
1996
Highly Cited
1996
Multivalent binding proteins, such as the yeast scaffold protein Sterile-5, coordinate the location of kinases by serving as… (More)
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