ACTA2 protein, human

Known as: ACTA2, actin, alpha 2, smooth muscle, aorta protein, human, Alpha-Cardiac Actin 
Actin, aortic smooth muscle (377 aa, ~42 kDa) is encoded by the human ACTA2 gene. This protein plays a role in the contraction of smooth muscle.
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
UNLABELLED The origin of fibrogenic cells in liver fibrosis remains controversial. We assessed the emerging concept that… (More)
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Highly Cited
2009
Highly Cited
2009
The vascular smooth muscle cell (SMC)-specific isoform of alpha-actin (ACTA2) is a major component of the contractile apparatus… (More)
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Highly Cited
2007
Highly Cited
2007
The major function of vascular smooth muscle cells (SMCs) is contraction to regulate blood pressure and flow. SMC contractile… (More)
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Highly Cited
2007
Highly Cited
2007
The major function of vascular smooth muscle cells (SMCs) is contraction to regulate blood pressure and flow. SMC contractile… (More)
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Highly Cited
2002
Highly Cited
2002
Endothelial cells of tumor vessels have well-documented alterations, but it is less clear whether pericytes on these vessels are… (More)
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Highly Cited
2001
Highly Cited
2001
We have examined the role of mechanical tension in myofibroblast differentiation using two in vivo rat models. In the first model… (More)
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Review
2000
Review
2000
Infarct scar, a requisite to the rebuilding of necrotic myocardium following myocardial infarction (MI), has long been considered… (More)
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Highly Cited
1998
Highly Cited
1998
We have derived a cardiac muscle cell line, designated HL-1, from the AT-1 mouse atrial cardiomyocyte tumor lineage. HL-1 cells… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The pathogenesis of pancreatic fibrosis is unknown. In the liver, stellate cells (vitamin A storing cells) play a… (More)
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Highly Cited
1993
Highly Cited
1993
Recent studies have shown that intracellular Ca2+ handling is abnormal in the myocardium of patients with end-stage heart failure… (More)
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