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connectin

Known as: Connectin [Chemical/Ingredient], Titin 
A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The… 
National Institutes of Health

Related topics

Related topics

17 relations
In BloodProcess of secretionTTN geneantagonists & inhibitors

Broader (2)

Muscle ProteinsScaffold protein

Narrower (6)

Myom1 protein, mouseTTN protein, humanTitin KinaseZDD4 protein, Bombyx mori

Papers overview

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Review
2004
Review
2004
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
The sarcomere contains, in addition to thin and thick filaments, a filament composed of the giant protein titin (also known as… 
Highly Cited
2003
Highly Cited
2003
Mechanics and structure of titin oligomers explored with atomic force microscopy.
Review
2000
Review
2000
Assembly of myofibrils in cardiac muscle cells.
How do myofibrils assemble in cardiac muscle cells? When does titin first assemble into myofibrils? What is the role of titin in… 
Highly Cited
2000
Highly Cited
2000
Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture.
An essential role of titin as a molecular ruler in sarcomerogenesis has been frequently discussed. In this study, we tested the… 
Highly Cited
1999
Highly Cited
1999
Modulation of sarcomere organization during embryonic stem cell-derived cardiomyocyte differentiation.
Highly Cited
1998
Highly Cited
1998
Two immunoglobulin‐like domains of the Z‐disc portion of titin interact in a conformation‐dependent way with telethonin
Highly Cited
1993
Highly Cited
1993
Titin folding energy and elasticity
Molecules of the giant protein titin are responsible for the passive elasticity and central A-band location of muscle myofibrils… 
Highly Cited
1988
Highly Cited
1988
Studies on cardiac myofibrillogenesis with antibodies to titin, actin, tropomyosin, and myosin
Cardiac myofibrillogenesis was examined in cultured chick cardiac cells by immunofluorescence using antibodies against titin… 
Highly Cited
1987
Highly Cited
1987
Immunocytochemical studies of cardiac myofibrillogenesis in early chick embryos. I. Presence of immunofluorescent titin spots in premyofibril stages
Our initial attempts to immunolabel intact myocardial walls of 4-12 somite stage chick embryos were hindered by the presence of… 
Highly Cited
1984
Highly Cited
1984
Cytoskeletal matrix in striated muscle: the role of titin, nebulin and intermediate filaments.
In this chapter, first I will briefly describe the molecular properties of titin and nebulin --two extremely large, myofibrillar… 
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