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Titin Kinase
Known as:
Kinase, Titin
, Titin
National Institutes of Health
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Related topics
Related topics
4 relations
TTN gene
TTN protein, human
Titin Ab:PrThr:Pt:Ser:Ord:IA
Broader (1)
connectin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling.
K. Hutchinson
,
Chandra Saripalli
,
C. Chung
,
H. Granzier
Journal of molecular and cellular cardiology
2015
Corpus ID: 3982652
Highly Cited
2015
Highly Cited
2015
Role of Titin Missense Variants in Dilated Cardiomyopathy
Rene L Begay
,
S. Graw
,
+12 authors
Matthew R. G. Taylor
Journal of the American Heart Association
2015
Corpus ID: 4450565
Background The titin gene (TTN) encodes the largest human protein, which plays a central role in sarcomere organization and…
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2014
2014
Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo
C. McKeown
,
Roberta B. Nowak
,
D. S. Gokhin
,
V. Fowler
Developmental dynamics : an official publication…
2014
Corpus ID: 205769432
BACKGROUND: We explored a function for tropomyosin (TM) in mammalian myofibril assembly and cardiac development by analyzing a…
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2010
2010
Exploring the conformation-regulated function of titin kinase by mechanical pump and probe experiments with single molecules.
E. M. Puchner
,
H. Gaub
Angewandte Chemie
2010
Corpus ID: 40002042
Protein function such as catalytic activity or molecular recognition is tightly coupled to the conformation and dynamics. Since…
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Review
2009
Review
2009
Titin-based mechanical signalling in normal and failing myocardium.
M. Krüger
,
W. Linke
Journal of molecular and cellular cardiology
2009
Corpus ID: 21453527
2009
2009
Altered contractility of skeletal muscle in mice deficient in titin's M-band region.
C. Ottenheijm
,
Carlos G. Hidalgo
,
Katharina Rost
,
M. Gotthardt
,
H. Granzier
Journal of molecular biology
2009
Corpus ID: 72274
Highly Cited
2003
Highly Cited
2003
The Hydrophilic Domain of Small Ankyrin-1 Interacts with the Two N-terminal Immunoglobulin Domains of Titin*
A. Kontrogianni-Konstantopoulos
,
R. Bloch
The Journal of Biological Chemistry
2003
Corpus ID: 1366811
Little is known about the mechanisms that organize the internal membrane systems in eukaryotic cells. We are addressing this…
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Highly Cited
2002
Highly Cited
2002
Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes
A. Natali
,
L. Wilson
,
M. Peckham
,
D. Turner
,
S. Harrison
,
E. White
The Journal of physiology
2002
Corpus ID: 11172517
Short‐term (6 weeks) voluntary wheel running exercise in young female rats that were in an active growth phase resulted in whole…
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Highly Cited
2001
Highly Cited
2001
Structural and functional studies of titin's fn3 modules reveal conserved surface patterns and binding to myosin S1--a possible role in the Frank-Starling mechanism of the heart.
C. Muhle-Goll
,
M. Habeck
,
O. Cazorla
,
M. Nilges
,
S. Labeit
,
H. Granzier
Journal of molecular biology
2001
Corpus ID: 21865626
The A-band part of titin, a striated-muscle specific protein spanning from the Z-line to the M-line, mainly consists of a well…
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Highly Cited
1998
Highly Cited
1998
The NH2 Terminus of Titin Spans the Z-Disc: Its Interaction with a Novel 19-kD Ligand (T-cap) Is Required for Sarcomeric Integrity
C. Gregorio
,
K. Trombitás
,
+9 authors
S. Labeit
The Journal of cell biology
1998
Corpus ID: 3038448
Titin is a giant elastic protein in vertebrate striated muscles with an unprecedented molecular mass of 3–4 megadaltons. Single…
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