FAQ

Titin Kinase

Known as: Kinase, Titin, Titin 
 

Topic mentions per year

Topic mentions per year

1988-2018
024619882018

Related topics

Related topics

3 relations
TTN geneTTN protein, human

Broader (1)

connectin

Related mentions per year

Related mentions per year

1975-2018
197019801990200020102020
Titin Kinase
connectin
TTN gene
TTN protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension.
Titin is a very large alternatively spliced protein that performs multiple functions in heart and skeletal muscles. A rat strain… (More)
Is this relevant?
2007
2007
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.
Titin is a giant protein that is in charge of the assembly and passive mechanical properties of the sarcomere. Cardiac titin… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Protein kinase-A phosphorylates titin in human heart muscle and reduces myofibrillar passive tension
Protein kinase-A (PKA) is activated during β-adrenergic stimulation of the heart and is known to phosphorylate several sarcomeric… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Phosphorylation of Titin Modulates Passive Stiffness of Cardiac Muscle in a Titin Isoform-dependent Manner
We investigated the effect of protein kinase A (PKA) on passive force in skinned cardiac tissues that express different isoforms… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts.
In the pathogenesis of dilated cardiomyopathy, cytoskeletal proteins play an important role. In this study, we analyzed titin… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2004
2004
Titin isoform changes in rat myocardium during development
Developmental changes in the alternative splicing patterns of titin were observed in rat cardiac muscle. Titin from 16-day fetal… (More)
  • table 1
  • figure 1
  • table 2
  • figure 3
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin
The zebrafish embryo is transparent and can tolerate absence of blood flow because its oxygen is delivered by diffusion rather… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Titin isoform switch in ischemic human heart disease.
BACKGROUND Ischemia-induced cardiomyopathy usually is accompanied by elevated left ventricular end-diastolic pressure, which… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2002
2002
Different molecular mechanics displayed by titin's constitutively and differentially expressed tandem Ig segments.
Titin is a giant elastic protein responsible for passive force generated by the stretched striated-muscle sarcomere. Passive… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1996
1996
Nonuniform elasticity of titin in cardiac myocytes: a study using immunoelectron microscopy and cellular mechanics.
Titin (also known as connectin) is a muscle-specific giant protein found inside the sarcomere, spanning from the Z-line to the M… (More)
Is this relevant?