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TTN protein, human

Known as: CMD1G protein, human, EC 2.7.11.1, Titin 
Titin (34350 aa, ~3816 kDa) is encoded by the human TTN gene. This protein plays a role in muscle filament structure and contraction.
National Institutes of Health

Related topics

Related topics

24 relations
Actin myofilamentCell MovementChromosome CondensationCytokinesis

Broader (1)

connectin

Papers overview

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Review
2004
Review
2004
Role of the giant elastic protein titin in the Frank-Starling mechanism of the heart.
Increased ventricular volume enhances the systolic performance, a phenomenon known as Frank-Starling's law of the heart. At its… 
Highly Cited
2002
Highly Cited
2002
Titin and nebulin content in human skeletal muscle following eccentric resistance exercise
We measured titin and nebulin content in muscle biopsies from the vastus lateralis before and 24 h after one bout of high… 
2000
2000
Effects of Corticosterone on Connectin Content and Protein Breakdown in Rat Skeletal Muscle
We examined the effects of a glucocorticoid, corticosterone, on calpain activity, connectin content and protein breakdown in rat… 
1993
1993
Dynamics of actin and assembly of connectin (titin) during myofibrillogenesis in embryonic chick cardiac muscle cells in vitro
Immunogold electron microscopy of cardiac myocytes microinjected with biotin‐labeled actin showed that gold labeling was first… 
Review
1992
Review
1992
Non-enzymatic weakening of myofibrillar structures during conditioning of meat: calcium ions at 0.1 mM and their effect on meat tenderization.
Review
1986
Review
1986
Connectin, an elastic filamentous protein of striated muscle.
1986
1986
EFFECTS OF MILD TRYPSIN TREATMENT ON THE PASSIVE TENSION GENERATION AND CONNECTIN SPLITTING IN STRETCHED SKINNED FIBERS FROM FROG SKELETAL MUSCLE MUSCLE
When skinned fibers from frog semitendinous muscle were mildly treated with trypsin, passive tension generation was remarkably… 
Highly Cited
1985
Highly Cited
1985
Connectin filaments link thick filaments and Z lines in frog skeletal muscle as revealed by immunoelectron microscopy
In an earlier study connectin, an elastic protein of striated muscle, was found to be associated with "gap filaments" originating… 
1983
1983
Preparation of native connectin from chicken breast muscle.
Connectin, an elastic protein of striated muscle, was isolated in a native state from chicken breast muscle. Myofibrils were well… 
Highly Cited
1979
Highly Cited
1979
Post-mortem changes in skeletal muscle connectin.
Changes in connectin and elasticity of skeletal muscle were determined during post-mortem ageing. The amount of connectin… 
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