TTN gene

Known as: TITIN, FLJ32040, MYLK5 
This gene plays a role in sarcomere structure.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0204019842018

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Dilated cardiomyopathy and hypertrophic cardiomyopathy arise from mutations in many genes. TTN, the gene encoding the… (More)
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Highly Cited
2003
Highly Cited
2003
Titin (also known as connectin) is a giant protein with a wide range of cellular functions, including providing muscle cells with… (More)
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Highly Cited
2003
Highly Cited
2003
Individual molecules of the giant protein titin span the A-bands and I-bands that make up striated muscle. The I-band region of… (More)
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Highly Cited
2002
Highly Cited
2002
Tibial muscular dystrophy (TMD) is an autosomal dominant late-onset distal myopathy linked to chromosome 2q31. The linked region… (More)
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Highly Cited
2002
Highly Cited
2002
Congestive heart failure (CHF) can result from various disease states with inadequate cardiac output. CHF due to dilated… (More)
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Highly Cited
2001
Highly Cited
2001
We studied the effect of titin-based passive force on the length dependence of activation of cardiac myocytes to explore whether… (More)
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Highly Cited
1996
Highly Cited
1996
When relaxed after contraction, isolated cardiac myocytes quickly relengthen back to their slack length. The molecular basis of… (More)
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Highly Cited
1995
Highly Cited
1995
In addition to thick and thin filaments, vertebrate striated muscle contains a third filament system formed by the giant protein… (More)
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Highly Cited
1992
Highly Cited
1992
When relaxed striated muscle cells are stretched, a resting tension is produced which is thought to arise from stretching long… (More)
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Highly Cited
1989
Highly Cited
1989
The protein titin has been localized by electron microscopy of myofibrils labelled with monoclonal antibodies. The data are… (More)
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