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Recombinant Interleukin-4

Known as: BCGF, RHIL-4, BCSF 1 
A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4… 
National Institutes of Health

Related topics

Related topics

14 relations
B-CELL GROWTH FACTORB-Cell ActivationCytokine Receptor ActivationCytotoxic T-Lymphocytes

Broader (1)

Interleukin-4

Papers overview

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1999
1999
CD4+ T Cells Which React to the Leishmania major LACK Antigen Rapidly Secrete Interleukin-4 and Are Detrimental to the Host in Resistant B10.D2 Mice
ABSTRACT Leishmania major induces the rapid production of interleukin-4 (IL-4) in both susceptible BALB/c and resistant B10.D2… 
1999
1999
Decrease in the prevalence of IL-4-producing CD4+ T cells in patients with advanced stage of primary biliary cirrhosis
OBJECTIVE:To elucidate the precise immunological features in primary biliary cirrhosis (PBC), we examined the relative prevalence… 
1998
1998
Inhibition of interleukin-4 and interleukin-13 release from immunologically activated human basophils due to the actions of anti-allergic drugs
Human basophils have recently been shown to rapidly produce and release interleukin (IL-)4 and IL-13 as well as histamine and… 
1998
1998
The role of IL-4 and IL-10 cytokines in controlling an anti-tumor response in vivo.
The effect of systemic administration of anti-inflammatory cytokines (IL-4 and IL-10) on the development and maintenance of an… 
1997
1997
Eosinophils and IgE receptors: a continuing controversy.
phils produce cytokines, such as interleukin-4 (IL-4) and D IL-5, which are potentially important in the recruitment of URING THE… 
1995
1995
An antagonistic mutant of interleukin-4 fails to recruit gamma c into the receptor complex. Characterization by specific crosslinking.
The receptor for interleukin-4 (IL-4) appears to be a heterodimer of the IL-4-binding protein IL-4R alpha and the gamma c chain… 
1991
1991
Experimental and theoretical studies of the three‐dimensional structure of human interleukin‐4
The structure of human interleukin 4 (IL‐4) was predicted utilizing a series of experimental and theoretical techniques. Circular… 
1991
1991
Interleukin-4-induced IgG subclass and IgE secretion by mononuclear cells from atopic donors.
To investigate the effect of interleukin-4 (IL-4) on the secretion of IgG subclasses and IgE in atopic individuals, peripheral… 
Highly Cited
1985
Highly Cited
1985
Purification of human B cell growth factor.
Human B cell growth factor (BCGF, 12,000 to 14,000 daltons) has been purified from lectin-stimulated, peripheral blood… 
1985
1985
T cell-derived B cell growth factor(s) can induce stimulation of both resting and activated B cells.
The effects of a preparation containing partially purified, EL4-derived B cell growth factor(s) (BCGF) on B cell growth and…