Recombinant Interleukin-4

Known as: BCGF, RHIL-4, BCSF 1 
A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
05010015019862018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
BACKGROUND Dupilumab, a fully human monoclonal antibody that blocks interleukin-4 and interleukin-13, has shown efficacy in… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Eosinophils are associated with helminth immunity and allergy, often in conjunction with alternatively activated macrophages… (More)
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Tumor-associated macrophages (TAMs) are alternatively activated cells induced by interleukin-4 (IL-4)-releasing CD4+ T cells… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Calcium-dependent chloride channels are required for normal electrolyte and fluid secretion, olfactory perception, and neuronal… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Activated T lymphocytes differentiate into effector cells tailored to meet disparate challenges to host integrity. For example… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The pathogenesis of asthma reflects, in part, the activity of T cell cytokines. Murine models support participation of… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1997
Highly Cited
1997
OBJECTIVE To examine the role of endogenous interleukin-4 (IL-4) and interleukin-10 (IL-10) and the therapeutic effect of the… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
A lymphocyte population that expresses surface markers found on T cells and natural killer (NK) cells secretes large amounts of… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Murine interleukin-4 (IL-4) exhibits potent antitumor activity when present at the site of tumor cell challenge. Associated with… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
The generation of antigen-specific antitumor immunity is the ultimate goal in cancer immunotherapy. When cells from a… (More)
Is this relevant?