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Cytokine Receptor Activation

Any interaction between a cognate ligand and any of a series of cytokine receptors. Activation of cytokine receptors is involved in regulation of the… Expand
National Institutes of Health

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Aerosol SargramostimAerosolized AldesleukinAldesleukinC-C Chemokine Receptor Type 2
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
Activated by interaction Cytokines trigger immune responses when they bind to their cognate receptors. Class I cytokine receptors… Expand
2019
2019
The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3.
Bacteria masterfully co-opt and subvert host signal transduction. As a paradigmatic example, Salmonella uses two type-3 secretion… Expand
2019
2019
The expression and clinical significance of ENPP2 in acute myeloid leukemia
Objective To analyze the expression and clinical significance of exonucleotide pyrophosphatase/phosphodiesterase family member 2… Expand
2012
2012
Targeted immunosuppression: no longer naïve.
Naive T cells patrol the body in search of their cognate antigen. However, it has become better appreciated that the outcome of… Expand
Review
2010
Review
2010
Molecular basis of cytokine receptor activation
Cytokines are secreted soluble peptides that precisely regulate multiple cellular functions. Amongst these the GM‐CSF/IL‐3/IL‐5… Expand
Highly Cited
2008
Highly Cited
2008
Redox regulation of interleukin-4 signaling.
The physiologic control of cytokine receptor activation is primarily mediated by reciprocal activation of receptor-associated… Expand
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2008
2008
Immunity Reactive Oxygen Species Promote IL-4 Signaling
Pankaj Sharma,1,6 Rikhia Chakraborty,1,2,6 Lu Wang,3 Booki Min,3 Michel L. Tremblay,4 Tsukasa Kawahara,5 J. David Lambeth,5 and S… Expand
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Review
2002
Review
2002
Molecular mechanisms of cytokine receptor activation.
Cytokine receptors are transmembrane proteins that transmit a signal into the cell upon ligand binding. Commonly, these molecules… Expand
Review
1997
Review
1997
The structural and functional basis of cytokine receptor activation: lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5…
CYTOKINE RECEPTORS are cell-surface glycoproteins that bind specifically to cytokines and transduce their signals. These… Expand
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Review
1997
Review
1997
Receptors of the cytokine superfamily: mechanisms of activation and involvement in disease.
Cytokine receptors are members of a diverse family of proteins that serve the dual function of recognizing their cognate ligands… Expand
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