C-C Chemokine Receptor Type 2

Known as: CCR2, CC-CKR-2, MCP-1-R 
C-C chemokine receptor type 2 (374 aa, ~42 kDa) is encoded by the human CCR2 gene. This protein plays a role in both cytokine binding and receptor… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
West Nile virus (WNV) is a re-emerging pathogen responsible for outbreaks of fatal meningoencephalitis in humans. Previous… (More)
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Highly Cited
2008
Highly Cited
2008
The enteric pathogen Toxoplasma gondii is controlled by a vigorous innate T helper 1 (Th1) cell response in the murine model. We… (More)
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Highly Cited
2007
Highly Cited
2007
Adipose tissue macrophages (ATMs) infiltrate adipose tissue during obesity and contribute to insulin resistance. We hypothesized… (More)
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Highly Cited
2007
Highly Cited
2007
Microglia are the principal immune cells of the brain. In Alzheimer disease, these brain mononuclear phagocytes are recruited… (More)
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Highly Cited
2006
Highly Cited
2006
The C-C motif chemokine receptor-2 (CCR2) regulates monocyte and macrophage recruitment and is necessary for macrophage-dependent… (More)
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Highly Cited
2004
Highly Cited
2004
The prevailing paradigm is that in human rheumatoid arthritis (RA), the accumulation of monocytes and T cells in the joint… (More)
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Highly Cited
2003
Highly Cited
2003
The study and treatment of age-related macular degeneration (AMD), a leading cause of blindness, has been hampered by a lack of… (More)
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Highly Cited
2002
Highly Cited
2002
Fibrosis is a common outcome of chronic inflammation or injury. Pulmonary fibrosis may be the result of abnormal repair after an… (More)
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Highly Cited
2000
Highly Cited
2000
Monocyte recruitment to the central nervous system (CNS) is a necessary step in the development of pathologic inflammatory… (More)
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Highly Cited
1997
Highly Cited
1997
Chemokines are a structurally related family of cytokines that are important for leukocyte trafficking. The C-C chemokine… (More)
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