C-C Chemokine Receptor Type 2
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Cognitive decline accompanies acute illness and surgery, especially in the elderly. Surgery engages the innate immune system that… Expand In addition to liver‐resident Kupffer cells, infiltrating immune cells have recently been linked to the development of liver… Expand OBJECTIVE—To establish the mechanism of the phenotypic switch of adipose tissue macrophages (ATMs) from an alternatively… Expand The enteric pathogen Toxoplasma gondii is controlled by a vigorous innate T helper 1 (Th1) cell response in the murine model. We… Expand Adipose tissue macrophages (ATMs) infiltrate adipose tissue during obesity and contribute to insulin resistance. We hypothesized… Expand Microglia are the principal immune cells of the brain. In Alzheimer disease, these brain mononuclear phagocytes are recruited… Expand The C-C motif chemokine receptor-2 (CCR2) regulates monocyte and macrophage recruitment and is necessary for macrophage-dependent… Expand The study and treatment of age-related macular degeneration (AMD), a leading cause of blindness, has been hampered by a lack of… Expand Monocyte recruitment to the central nervous system (CNS) is a necessary step in the development of pathologic inflammatory… Expand Chemokines are a structurally related family of cytokines that are important for leukocyte trafficking. The C-C chemokine… Expand