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C-C Chemokine Receptor Type 2

Known as: CCR2, CC-CKR-2, MCP-1-R 
C-C chemokine receptor type 2 (374 aa, ~42 kDa) is encoded by the human CCR2 gene. This protein plays a role in both cytokine binding and receptor… 
National Institutes of Health

Related topics

Related topics

23 relations
CCR2 geneCCR2 wt AlleleChemokine Receptor GeneChemotaxis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Absence of CCR2 results in an inflammaging environment in young mice with age‐independent impairments in muscle regeneration
Skeletal muscle regeneration requires coordination between dynamic cellular populations and tissue microenvironments. Macrophages… 
2016
2016
The Dual Ccr2/Ccr5 Antagonist Cenicriviroc Ameliorates Steatohepatitis and Fibrosis in Vivo by Inhibiting the Infiltration of Inflammatory Monocytes into Injured Liver
2012
2012
The Chemokine Receptor CCR2 Is Not Required for Successful Initiation of Labor in Mice1
ABSTRACT Chemokine-driven neutrophil and monocyte recruitment into the uterus and cervix has been proposed to initiate labor… 
2011
2011
Ligand supported homology modeling and docking evaluation of CCR2: docked pose selection by consensus scoring
Chemokine receptor 2 (CCR2) is a G-protein coupled receptor (GPCR) and a crucial target for various inflammatory and autoimmune… 
2011
2011
Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy+Apoe−/− mouse model of the metabolic syndrome
Aims/hypothesisChemokines and their receptors such as chemokine (C-C motif) receptor 2 (CCR2) may contribute to the pathogenesis… 
2010
2010
CCR2 deficiency results in increased osteolysis in experimental periapical lesions in mice.
2010
2010
A competitive binding study of chemokine, sulfated receptor, and glycosaminoglycan interactions by nano-electrospray ionization mass spectrometry.
2009
2009
Potential implications for epigenetic regulation of carotenoid biosynthesis during root and shoot development
Major regulators of carotenoid biosynthesis have remained rather elusive even though the flux through the branch in the… 
2006
2006
Identification of a repetitive sequence belonging to a PPE gene of Mycobacterium tuberculosis and its use in diagnosis of tuberculosis.
A repetitive sequence specific to Mycobacterium tuberculosis was isolated from a lambda gt11 library of M. tuberculosis by DNA… 
Highly Cited
1999
Highly Cited
1999
Role of the First Extracellular Loop in the Functional Activation of CCR2
The physiological cellular responses to monocyte chemoattractant protein-1 (MCP-1), a potent chemotactic and activating factor… 
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