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CCR2 wt Allele
Known as:
CMKBR2
, CCR2A
, CC-CKR-2
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Human CCR2 wild-type allele is located in the vicinity of 3p21.31 and is approximately 7 kb in length. This allele, which encodes C-C chemokine…
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National Institutes of Health
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Related topics
Related topics
15 relations
3p21.31
C-C Chemokine Receptor Type 2
Chemotaxis
Cytokine Receptor Activation
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Broader (1)
CCR2 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Enhanced Tumor Trafficking of GD2 Chimeric Antigen Receptor T Cells by Expression of the Chemokine Receptor CCR2b
J. Craddock
,
An Lu
,
+4 authors
A. Foster
Journal of immunotherapy
2010
Corpus ID: 21818208
For adoptive T-cell therapy to be effective against solid tumors, tumor-specific T cells must be able to migrate to the tumor…
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Highly Cited
2007
Highly Cited
2007
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature
Z. Miao
,
K. Luker
,
+9 authors
T. Schall
Proceedings of the National Academy of Sciences
2007
Corpus ID: 15892916
Chemokines and chemokine receptors have been posited to have important roles in several common malignancies, including breast and…
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Highly Cited
2005
Highly Cited
2005
Evidence for Negative Binding Cooperativity within CCR5-CCR2b Heterodimers
Laïla El-Asmar
,
J. Springael
,
S. Ballet
,
Eneko Urizar Andrieu
,
G. Vassart
,
M. Parmentier
Molecular Pharmacology
2005
Corpus ID: 2530571
It is well established that most G protein-coupled receptors are able to form homo- and heterodimers, although the functional…
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Highly Cited
2004
Highly Cited
2004
Cytoreductive surgery and intraperitoneal chemohyperthermia for peritoneal carcinomatosis arising from gastric cancer.
O. Glehen
,
V. Schreiber
,
+6 authors
F. Gilly
Archives of surgery
2004
Corpus ID: 3153487
HYPOTHESIS The most common cause of palliative resection and recurrence in gastric cancer is peritoneal seeding. This study…
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Highly Cited
1998
Highly Cited
1998
Monomeric Monocyte Chemoattractant Protein-1 (MCP-1) Binds and Activates the MCP-1 Receptor CCR2B*
C. Paavola
,
S. Hemmerich
,
+10 authors
T. Handel
The Journal of Biological Chemistry
1998
Corpus ID: 2952064
To address the role of dimerization in the function of the monocyte chemoattractant protein-1, MCP-1, we mutated residues that…
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Highly Cited
1998
Highly Cited
1998
The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.
M. Mellado
,
J. Rodríguez-Frade
,
+6 authors
C. Martínez-A
Journal of immunology
1998
Corpus ID: 27412068
The chemokines are a growing family of low m.w., 70- to 80-residue proinflammatory cytokines that operate by interacting with G…
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Highly Cited
1996
Highly Cited
1996
Molecular cloning and functional expression of a new human CC-chemokine receptor gene.
M. Samson
,
O. Labbé
,
C. Mollereau
,
G. Vassart
,
M. Parmentier
Biochemistry
1996
Corpus ID: 7751797
The cloning of several receptors activated by either CC or CXC chemokines and belonging to the G protein-coupled family of…
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Highly Cited
1996
Highly Cited
1996
Molecular Cloning and Functional Characterization of a Novel Human CC Chemokine Receptor (CCR5) for RANTES, MIP-1β, and MIP-1α*
C. Raport
,
J. Gosling
,
V. Schweickart
,
P. Gray
,
I. Charo
The Journal of Biological Chemistry
1996
Corpus ID: 44745206
Chemokines affect leukocyte chemotactic and activation activities through specific G protein-coupled receptors. In an effort to…
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Highly Cited
1996
Highly Cited
1996
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes
P. Loetscher
,
M. Seitz
,
M. Baggiolini
,
B. Moser
The Journal of experimental medicine
1996
Corpus ID: 12137748
Several studies have shown that CC chemokines attract T lymphocytes, and that CD45RO+, memory phenotype cells are considered to…
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Highly Cited
1996
Highly Cited
1996
Multiple Extracellular Elements of CCR5 and HIV-1 Entry: Dissociation from Response to Chemokines
R. Atchison
,
J. Gosling
,
+4 authors
M. Goldsmith
Science
1996
Corpus ID: 43153538
The human β-chemokine receptor CCR5 is an important cofactor for entry of human immunodeficiency virus-type 1 (HIV-1). The murine…
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