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For adoptive T-cell therapy to be effective against solid tumors, tumor-specific T cells must be able to migrate to the tumor… Expand Chemokines and chemokine receptors have been posited to have important roles in several common malignancies, including breast and… Expand It is well established that most G protein-coupled receptors are able to form homo- and heterodimers, although the functional… Expand HYPOTHESIS
The most common cause of palliative resection and recurrence in gastric cancer is peritoneal seeding. This study… Expand The burgeoning information on the human genome creates opportunities and challenges for studies of disease associations. Because… Expand ABSTRACT The chemokine receptor CCR5 and to a lesser extent CCR3 and CCR2b have been shown to serve as coreceptors for human… Expand The cloning of several receptors activated by either CC or CXC chemokines and belonging to the G protein-coupled family of… Expand Chemokines affect leukocyte chemotactic and activation activities through specific G protein-coupled receptors. In an effort to… Expand Several studies have shown that CC chemokines attract T lymphocytes, and that CD45RO+, memory phenotype cells are considered to… Expand The human β-chemokine receptor CCR5 is an important cofactor for entry of human immunodeficiency virus-type 1 (HIV-1). The murine… Expand