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CCR2 gene

Known as: CCR2, CMKBR2, CCR2A 
This gene plays a role in chemokine signaling.
National Institutes of Health

Related topics

Related topics

14 relations
C-C Chemokine Receptor Type 2ChemotaxisCytokine Receptor ActivationCytokine Signaling

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CCR2 wt Allele

Papers overview

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Review
2013
Review
2013
Chemokine Systems Link Obesity to Insulin Resistance
Obesity is a state of chronic low-grade systemic inflammation. This chronic inflammation is deeply involved in insulin resistance… 
Highly Cited
2004
Highly Cited
2004
A CCR2-V64I polymorphism affects stability of CCR2A isoform
Objective: A valine to isoleucine substitution at position 64 of CCR2 (CCR2-64I) is associated with a delay in progression to… 
Highly Cited
2000
Highly Cited
2000
Functional Differences Between Monocyte Chemotactic Protein-1 Receptor A and Monocyte Chemotactic Protein-1 Receptor B Expressed in a Jurkat T Cell
The monocyte chemotactic protein-1 (MCP-1) receptor (MCP-1R) is expressed on monocytes, a subpopulation of memory T lymphocytes… 
Highly Cited
1999
Highly Cited
1999
CXC and CC Chemokine Receptors on Coronary and Brain Endothelia
BackgroundChemokine receptors on leukocytes play a key role in inflammation and HIV-1 infection. Chemokine receptors on… 
Highly Cited
1997
Highly Cited
1997
STRL33, A Novel Chemokine Receptor–like Protein, Functions as a Fusion Cofactor for Both Macrophage-tropic and T Cell Line–tropic HIV-1
The chemokine receptors CXCR4, CCR2B, CCR3, and CCR5 have recently been shown to serve along with CD4 as coreceptors for HIV-1… 
Highly Cited
1997
Highly Cited
1997
Monocyte Chemotactic Protein-2 (MCP-2) Uses CCR1 AND CCR2B as Its Functional Receptors*
Monocyte chemotactic protein (MCP)-2 is a member of the C-C chemokine subfamily, which shares more than 60% sequence homology… 
Highly Cited
1997
Highly Cited
1997
CC Chemokine Receptor 5-Mediated Signaling and HIV-1 Co-receptor Activity Share Common Structural Determinants
There is a close correspondence between the ability of RANTES and macrophage inflammatory proteins 1α and 1β to activate CC… 
Highly Cited
1996
Highly Cited
1996
The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3.
The five human CC-chemokine receptors functionally characterized to date were mapped by using a radiation hybrid panel and YAC… 
Highly Cited
1996
Highly Cited
1996
Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.
Several chemokine receptors have been cloned and shown to belong to a superfamily of seven transmembrane, G protein-coupled… 
Highly Cited
1995
Highly Cited
1995
Monocyte Chemoattractant Protein-3 Is a Functional Ligand for CC Chemokine Receptors 1 and 2B (*)
The CC chemokine monocyte chemoattractant protein-3 (MCP-3) activates human monocytes, lymphocytes, basophils, and eosinophils… 
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