Cytokine Signaling

Known as: Cytokine Signal Transduction 
Any environment-to-cell cummunication that involves cytokines. This process is involved in immune function.
National Institutes of Health

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Papers overview

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Highly Cited
2010
Highly Cited
2010
MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene.
MicroRNA-155 (miR-155) is overexpressed in many human cancers; however, the mechanisms by which miR-155 functions as a putative… (More)
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Highly Cited
2010
Highly Cited
2010
Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1.
Effective recognition of viral infection and subsequent triggering of antiviral innate immune responses are essential for the… (More)
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Review
2008
Review
2008
Cytokine signaling modules in inflammatory responses.
Cytokine signaling via a restricted number of Jak-Stat pathways positively and negatively regulates all cell types involved in… (More)
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Highly Cited
2008
Highly Cited
2008
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.
Appropriate development of regulatory T (Treg) cells is necessary to prevent autoimmunity. Neonatal mice, unlike adults, lack… (More)
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Highly Cited
2004
Highly Cited
2004
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.
Insulin resistance is a pathophysiological component of type 2 diabetes and obesity and also occurs in states of stress… (More)
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Review
2004
Review
2004
Inhibitors of cytokine signal transduction.
Cytokines are secreted proteins that regulate diverse biological functions by binding to receptors at the cell surface to… (More)
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Review
2003
Review
2003
Regulation of cytokine signaling by SOCS family molecules.
Cytokine signaling is dependent on the activation of intracellular molecules, including JAKs (Janus family kinases) and STATs… (More)
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Highly Cited
2003
Highly Cited
2003
Twist Regulates Cytokine Gene Expression through a Negative Feedback Loop that Represses NF-κB Activity
During Drosophila embryogenesis, the dorsal transcription factor activates the expression of twist, a transcription factor… (More)
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Review
2001
Review
2001
Negative regulation of cytokine signaling.
Cytokines use complex signaling cascades to elicit their biological effects, many of which involve phosphorylation as a mechanism… (More)
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Review
2000
Review
2000
Negative regulation of cytokine signaling pathways.
The Janus family of protein tyrosine kinases (JAKs) and STAT transcription factors regulate cellular processes involved in cell… (More)
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