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CCL17 gene

Known as: THYMUS AND ACTIVATION-REGULATED CHEMOKINE, ABCD-2, CHEMOKINE, CC MOTIF, LIGAND 17 
This gene is involved in several processes such as T cell development in the thymus and mature T cell regulation.
National Institutes of Health

Related topics

Related topics

11 relations
CCL17 protein, humanCCL17 wt AlleleChemotaxisCytokine Receptor Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4
BACKGROUND AND PURPOSE The operational model provides a key conceptual framework for the analysis of pharmacological data… 
Highly Cited
2006
Highly Cited
2006
Interleukin-17 is a negative regulator of established allergic asthma
T helper (Th)17 cells producing interleukin (IL)-17 play a role in autoimmune and allergic inflammation. Here, we show that IL-23… 
2003
2003
Hypereosinophilia with abnormal T cells, trisomy 7 and elevated TARC serum level.
The idiopathic hypereosinophilic syndrome (HES) is a rare heterogeneous disorder, characterized by persistent blood eosinophilia… 
Highly Cited
2002
Highly Cited
2002
In vitro assessment of chemokine receptor‐ligand interactions mediating mouse eosinophil migration
Eosinophil migration from circulation is controlled, in part, by chemokines through a family of G‐protein‐coupled chemokine… 
Highly Cited
2001
Highly Cited
2001
Intervention of Thymus and Activation-Regulated Chemokine Attenuates the Development of Allergic Airway Inflammation and Hyperresponsiveness in Mice1
Thymus- and activation-regulated chemokine (TARC; CCL17) is a lymphocyte-directed CC chemokine that specifically chemoattracts CC… 
Highly Cited
2001
Highly Cited
2001
Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts.
The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on T helper (Th)2-type CD4 T cells. Allergic airway… 
2001
2001
Clonal Th2 cells associated with chronic hypereosinophilia: TARC‐induced CCR4 down‐regulation in vivo
We analyzed the expression of chemokine receptors on clonal Th2‐type CD4+CD3– lymphocytes isolated from blood of two patients… 
Highly Cited
2000
Highly Cited
2000
A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin.
Atopic dermatitis is an inflammatory skin disease in which the inflammation is characterized by the influx of lymphocytes into… 
Highly Cited
1999
Highly Cited
1999
Three chemokines with potential functions in T lymphocyte‐independent and ‐dependent B lymphocyte stimulation
Three clustered mouse chemokine genes, ABCD‐1, ‐2 and ‐3, are all expressed highly in dendritic cells and, at various levels, in… 
Highly Cited
1996
Highly Cited
1996
Molecular Cloning of a Novel T Cell-directed CC Chemokine Expressed in Thymus by Signal Sequence Trap Using Epstein-Barr Virus Vector*
Precursors of most secreted and cell surface molecules carry signal sequences at their amino termini. Here we describe an… 
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