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BACKGROUND AND PURPOSE The operational model provides a key conceptual framework for the analysis of pharmacological data… Expand Patients with atopic dermatitis (AD) have significantly reduced plasma cAMP levels, and the cAMP level is correlated with the… Expand T helper (Th)17 cells producing interleukin (IL)-17 play a role in autoimmune and allergic inflammation. Here, we show that IL-23… Expand Abstract: TARC/CCL17 (thymus‐ and activation‐regulated chemokine) is a CC chemokine, which binds to the CC chemokine receptor‐4… Expand Eosinophil migration from circulation is controlled, in part, by chemokines through a family of G‐protein‐coupled chemokine… Expand Thymus- and activation-regulated chemokine (TARC; CCL17) is a lymphocyte-directed CC chemokine that specifically chemoattracts CC… Expand The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on T helper (Th)2-type CD4 T cells. Allergic airway… Expand Atopic dermatitis is an inflammatory skin disease in which the inflammation is characterized by the influx of lymphocytes into… Expand Three clustered mouse chemokine genes, ABCD‐1, ‐2 and ‐3, are all expressed highly in dendritic cells and, at various levels, in… Expand Precursors of most secreted and cell surface molecules carry signal sequences at their amino termini. Here we describe an… Expand