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B-Cell Activation

Known as: B cell activation, B lymphocyte activation, B-lymphocyte activation 
A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface… 
National Institutes of Health

Related topics

Related topics

50 relations
APS GeneAntigensB-LymphocytesBCL2 gene

Narrower (1)

establishment of B cell polarity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Cell-specific regulation of the CD21 gene.
Highly Cited
1999
Highly Cited
1999
Autoantigen-Specific B Cell Activation in FAS-Deficient Rheumatoid Factor Immunoglobulin Transgenic Mice
In systemic autoimmune disease, self-tolerance fails, leading to autoantibody production. A central issue in immunology is to… 
Review
1997
Review
1997
B-cell activation versus tolerance--the central role of immunoglobulin receptor engagement and T-cell help.
The critical variables responsible for the decision between activation and tolerance in the B-cell compartment were studied in… 
Highly Cited
1995
Highly Cited
1995
Hematopoietic Cell Phosphatase Is Recruited to CD22 following B Cell Antigen Receptor Ligation (*)
Hematopoietic cell phosphatase is a nonreceptor protein tyrosine phosphatase that is preferentially expressed in hematopoietic… 
Highly Cited
1992
Highly Cited
1992
Differential increase of an alternatively polyadenylated mRNA species of murine CD40 upon B lymphocyte activation.
CD40 is an integral membrane glycoprotein found on the surface of human B lymphocytes. Antibodies specific for CD40 have been… 
Highly Cited
1991
Highly Cited
1991
Surface immunoglobulin crosslinking activates a tyrosine kinase pathway in B cells that is independent of protein kinase C.
It has been found that the principal biochemical pathway activated in B cells stimulated by antigen- or anti-immunoglobulin… 
Highly Cited
1989
Highly Cited
1989
Sequence of the Lyb-2 B-cell differentiation antigen defines a gene superfamily of receptors with inverted membrane orientation.
Lyb-2 is a mouse B-cell differentiation antigen expressed on the surface of pre-B cells and B cells but not on terminally… 
1984
1984
Role of cell surface immunoglobulin in B-lymphocyte activation.
The role of cell surface immunoglobulin in helper T-cell-dependent B-cell activation was analyzed using a B-cell lymphoma, CH12… 
Highly Cited
1983
Highly Cited
1983
T cell regulation of b cell activation. Cloned Lyt-1+2-T suppressor cells inhibit the major histocompatibility complex-restricted interaction of T helper cells with B cells and/or accessory cells
The present studies have identified cloned Lyt-1+2- T suppressor (Ts) cells that are both antigen specific and major… 
Highly Cited
1976
Highly Cited
1976
Fc receptor-mediated inhibition of murine B-lymphocyte activation
Immobilized antigen-antibody complexes are able to inhibit the mitogenic response of murine spleen cells to the B-cell mitogen 8… 
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