BCL2 gene

Known as: bcl-2 Gene, BCL2, Gene, bcl-2 
A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
020406019882018

Papers overview

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Highly Cited
2013
Highly Cited
2013
MYC rearrangements occur in 5% to 10% of diffuse large B-cell lymphomas (DLBCL) and confer an increased risk to cyclophosphamide… (More)
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Highly Cited
2010
Highly Cited
2010
Background:Breast cancer is heterogeneous and the existing prognostic classifiers are limited in accuracy, leading to unnecessary… (More)
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Highly Cited
2008
Highly Cited
2008
microRNAs are endogenous small noncoding RNAs that regulate gene expression negatively at posttranscriptional level. This latest… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The role of BCL2 as a predictor of survival in diffuse large B-cell lymphoma (DLBCL) is controversial. DLBCL is… (More)
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Highly Cited
2004
Highly Cited
2004
Gene expression profiling of diffuse large B-cell lymphoma (DLBCL) has revealed prognostically important subgroups: germinal… (More)
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Highly Cited
1998
Highly Cited
1998
Diffuse large B-cell lymphoma (DLCL) is characterized by a marked degree of morphologic and clinical heterogeneity. We studied… (More)
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Highly Cited
1997
Highly Cited
1997
Gene activation by translocation between an oncogene and an immunoglobulin heavy-chain gene, which leads to increased expression… (More)
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1996
1996
A main function attributed to the BCL2 protein is its ability to confer resistance against apoptosis. In addition to the… (More)
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Highly Cited
1991
Highly Cited
1991
The biological functions of the BCL2 gene were investigated in transgenic mice harboring human BCL2 cDNA under the control of an… (More)
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Highly Cited
1991
Highly Cited
1991
The BCL2 protooncogene encodes an inner mitochondrial membrane protein that blocks programmed cell death. BCL2 was isolated from… (More)
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