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BCL2 gene
Known as:
bcl-2 Gene
, BCL2
, Gene, bcl-2
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A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome…
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National Institutes of Health
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Related topics
Related topics
28 relations
Apoptosis
B-Cell Activation
BCL2 Ag:PrThr:Pt:Tiss:Ord:Immune stain
BCL2 Gene Rear Bld/T Ql
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c-bcl-2 Genes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
S. Pattingre
,
Amina T Tassa
,
+6 authors
B. Levine
Cell
2005
Corpus ID: 1616629
Highly Cited
2005
Highly Cited
2005
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T. Oltersdorf
,
S. Elmore
,
+30 authors
S. Rosenberg
Nature
2005
Corpus ID: 4335635
Proteins in the Bcl-2 family are central regulators of programmed cell death, and members that inhibit apoptosis, such as Bcl-XL…
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Highly Cited
1997
Highly Cited
1997
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
Jie Yang
,
X. Liu
,
+6 authors
Xiaodong Wang
Science
1997
Corpus ID: 32349676
Bcl-2 is an integral membrane protein located mainly on the outer membrane of mitochondria. Overexpression of Bcl-2 prevents…
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Highly Cited
1997
Highly Cited
1997
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
R. Kluck
,
E. Bossy‐Wetzel
,
D. Green
,
D. Newmeyer
Science
1997
Corpus ID: 8025067
In a cell-free apoptosis system, mitochondria spontaneously released cytochrome c, which activated DEVD-specific caspases…
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Highly Cited
1994
Highly Cited
1994
Disruption of epithelial cell-matrix interactions induces apoptosis
S. Frisch
,
H. Francis
The Journal of cell biology
1994
Corpus ID: 1906601
Cell-matrix interactions have major effects upon phenotypic features such as gene regulation, cytoskeletal structure…
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Highly Cited
1993
Highly Cited
1993
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
Zoltán N. Oltval
,
C. Milliman
,
S. Korsmeyer
Cell
1993
Corpus ID: 31151334
Highly Cited
1993
Highly Cited
1993
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
D. Hockenbery
,
Z. Oltvai
,
Xiao-Ming Yin
,
C. Milliman
,
S. Korsmeyer
Cell
1993
Corpus ID: 37004175
Highly Cited
1993
Highly Cited
1993
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
L. Boise
,
M. González-García
,
+6 authors
C. Thompson
Cell
1993
Corpus ID: 13542617
Highly Cited
1990
Highly Cited
1990
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
D. Hockenbery
,
G. Núñez
,
C. Milliman
,
R. Schreiber
,
S. Korsmeyer
Nature
1990
Corpus ID: 4253733
THE t(14; 18) chromosomal translocation of human follicular B-cell lymphoma juxtaposes the bcl-2 gene with the immunoglobulin…
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Review
1988
Review
1988
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
D. Vaux
,
S. Cory
,
Jerry M. Adams
Nature
1988
Corpus ID: 23593952
A common feature of follicular lymphoma, the most prevalent haematological malignancy in humans, is a chromosome translocation (t…
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