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BCL2 gene

Known as: bcl-2 Gene, BCL2, Gene, bcl-2 
A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Bax and Bak are members of the Bcl-2 family and core regulators of the intrinsic pathway of apoptosis. Upon apoptotic stimuli… Expand
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Review
2017
Review
2017
SR and hnRNP proteins were initially discovered as regulators of alternative splicing: the process of controlled removal of… Expand
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Review
2017
Review
2017
BACKGROUND The cJun-N-terminal-kinase (JNK) plays a central role in the cell stress response, with outcomes ranging from cell… Expand
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Highly Cited
2005
Highly Cited
2005
Apoptosis and autophagy are both tightly regulated biological processes that play a central role in tissue homeostasis… Expand
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Highly Cited
2005
Highly Cited
2005
Proteins in the Bcl-2 family are central regulators of programmed cell death, and members that inhibit apoptosis, such as Bcl-XL… Expand
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Highly Cited
1997
Highly Cited
1997
Bcl-2 is an integral membrane protein located mainly on the outer membrane of mitochondria. Overexpression of Bcl-2 prevents… Expand
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Highly Cited
1997
Highly Cited
1997
In a cell-free apoptosis system, mitochondria spontaneously released cytochrome c, which activated DEVD-specific caspases… Expand
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Highly Cited
1994
Highly Cited
1994
Cell-matrix interactions have major effects upon phenotypic features such as gene regulation, cytoskeletal structure… Expand
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Highly Cited
1993
Highly Cited
1993
Bcl-2 protein is able to repress a number of apoptotic death programs. To investigate the mechanism of Bcl-2's effect, we… Expand
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Highly Cited
1990
Highly Cited
1990
THE t(14; 18) chromosomal translocation of human follicular B-cell lymphoma juxtaposes the bcl-2 gene with the immunoglobulin… Expand
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