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Interleukin-4

Known as: BSF1 (B cell stimulating factor 1), BCGF, interleukin-4 (IL-4) 
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes… 
National Institutes of Health

Related topics

Related topics

29 relations

Broader (5)

Antineoplastic AgentsAntirheumatic AgentsHematopoietic Cell Growth FactorsImmunologic Adjuvants
B-CELL GROWTH FACTORHistocompatibility Antigens Class IIIL4 geneIn Blood

Narrower (6)

DAB(389)-interleukin 4Ph8 peptideRecombinant Interleukin-4interleukin-4, human

Papers overview

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2001
2001
CD 16 and CD 16 – human blood monocyte subsets differentiate in vitro to dendritic cells with different abilities to stimulate CD 4 T cells
Experimental protocols for cancer immunotherapy include the utilization of autologous monocytederived dendritic cells (moDC… 
1998
1998
The L3 of Brugia induces a T h 2-polarized response following activation of an IL-4-producing CD4 - CD8 - ab T cell population
Lymphatic filariasis in man is characterized by a profound bias in the immune response. Parasitespecific Th1 responses are… 
1998
1998
THE CELLULAR BASIS OF CARDIAC ALLOGRAFT REJECTION
allograft rejection in mice. Transplant Proc 1995; 27(1): 380. 40. Anderson GP, Coyle AJ. TH2 and “TH2-like” cells in allergy and… 
1994
1994
Inhibition of stem cell factor dependent formation of human mast cells by interleukin-3 and interleukin-4.
In murines, interleukins (IL) 3, 4, 9, and 10, nerve growth factor, and stem cell factor induce or promote growth and… 
1987
1987
Effects of antigens and lymphokines on early activation of single hapten-specific B lymphocytes.
An assay was developed to monitor early activation of single fluorescein-specific B cells obtained from the spleens of… 
1987
1987
Characterization of a keratinocyte-derived T cell growth factor distinct from interleukin 2 and B cell stimulatory factor 1.
Epidermal epithelial cells (keratinocytes) produce and secrete a variety of immunologically active cytokines. We have previously… 
Highly Cited
1986
Highly Cited
1986
BSF1 induces membrane protein phosphorylation but not phosphoinositide metabolism, Ca2+ mobilization, protein kinase C translocation, or membrane depolarization in resting murine B lymphocytes.
The findings presented in this study provide evidence that BSF1 receptors and mIg transmit signals via dissimilar transduction… 
1986
1986
Stimulating and differentiation factors for human B lymphocytes in systemic lupus erythematosus.
T cells from 18 untreated SLE patients produced significantly more B cell growth factor (BCGF) than did those from normal… 
1984
1984
Interleukin 1 induces proliferation in two distinct B cell subpopulations responsive to two different murine B cell growth factors.
Two distinct classes of B cell growth factor (BCGF) have been described. BCGF I induces proliferation of anti-IgM-activated B… 
Highly Cited
1983
Highly Cited
1983
Characterization of human B cell growth factor (BCGF) from cloned T cells or mitogen-stimulated T cells.
An assay system for the measurement of human BCGF was established by employing anti-id-stimulated B-CLL cells, anti-mu-stimulated…