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Receptor, Muscarinic M2

Known as: Receptor M2, Muscarinic, Muscarinic Receptors M2, Receptors M2, Muscarinic 
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth… 
National Institutes of Health

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Broader (1)

Muscarinic Acetylcholine Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Several correlated phenotypes, alcohol dependence, major depressive syndrome, and an endophenotype of electrophysiological… 
Highly Cited
1997
Highly Cited
1997
Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo
Urinary bladder smooth muscle is enriched with muscarinic receptors, the majority of which are of the M2 subtype whereas the… 
Highly Cited
1997
Highly Cited
1997
RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K+ channels
G protein gated inward rectifier K+ (GIRK) channels mediate hyperpolarizing postsynaptic potentials in the nervous system and in… 
Highly Cited
1995
Highly Cited
1995
Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins.
Activation of muscarinic acetylcholine receptors is primarily responsible for urinary bladder emptying. Because multiple subtypes… 
Highly Cited
1994
Highly Cited
1994
Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum.
Although the acute effects of organophosphorus esters are generally ascribed to inhibition of acetylcholinesterase, work in this… 
Highly Cited
1993
Highly Cited
1993
Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors.
We have tested the hypothesis that guanine-nucleotide-binding-protein-coupled receptors may be able to interact with each other… 
Highly Cited
1993
Highly Cited
1993
Association of m1 and m2 muscarinic receptor proteins with asymmetric synapses in the primate cerebral cortex: morphological evidence for cholinergic modulation of excitatory neurotransmission.
Muscarinic m1 receptors traditionally are considered to be postsynaptic to cholinergic fibers, while m2 receptors are largely… 
Highly Cited
1991
Highly Cited
1991
Distribution of m2 muscarinic receptors in rat brain using antisera selective for m2 receptors.
The DNA fragment encoding the third intracellular loop of rat m2 muscarinic receptor was fused to the gene for staphylococcal… 
Highly Cited
1990
Highly Cited
1990
Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes.
Relatively little is understood concerning the mechanisms by which subtypes of receptors, G proteins and effector enzymes… 
Highly Cited
1987
Highly Cited
1987
Primary structure and biochemical properties of an M2 muscarinic receptor.
A partial amino acid sequence obtained for porcine atrial muscarinic acetylcholine receptor was used to isolate complementary DNA… 
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